GABRA5 antibody (Middle Region)

Catalog No. ABIN404976

Product Details anti-GABRA5 Antibody

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Rabbit, Guinea Pig, Horse, Cow, Dog, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABRA5 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Sequence: GTSNTTSVSV KPSEEKTSES KKTYNSISKI DKMSRIVFPV LFGTFNLVYW

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%

Characteristics: This is a rabbit polyclonal antibody against GABRA5. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GABRA5

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 462 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABRA5

Target: GABRA5 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 5 (GABRA5))

Alternative Name: GABRA5 (GABRA5 Products)

Synonyms: GABRA5 antibody, si:dkey-93p24.1 antibody, A230018I05Rik antibody, gamma-aminobutyric acid type A receptor alpha5 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, alpha 5 antibody, gamma-aminobutyric acid type A receptor alpha 5 subunit antibody, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 5 antibody, gamma-aminobutyric acid receptor subunit alpha-5 antibody, GABRA5 antibody, gabra5 antibody, Gabra5 antibody, LOC100653497 antibody

Background: GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described.GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Transcript variants utilizing three different alternative non-coding first exons have been described. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC138184
Protein Interaction Partner: UBC,
Protein Size: 462

Molecular Weight: 49 kDa

Gene ID: 2558

NCBI Accession: NM_000810, NP_000801

UniProt: P31644

Pathways: Sensory Perception of Sound, Synaptic Membrane