PKDREJ antibody (Middle Region)

Catalog No. ABIN404982

Product Details anti-PKDREJ Antibody

Target: PKDREJ (Polycystic Kidney Disease and Receptor for Egg Jelly-Related Protein (PKDREJ))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PKDREJ antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GVADNGSVLE ITPDVAEVYL VRKNLTFAAF NLTVGPNSEV DGSLKKTTGG

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against PKDREJ. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PKDREJ

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 2253 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PKDREJ

Target: PKDREJ (Polycystic Kidney Disease and Receptor for Egg Jelly-Related Protein (PKDREJ))

Alternative Name: PKDREJ (PKDREJ Products)

Synonyms: polycystin family receptor for egg jelly antibody, polycystic kidney disease (polycystin) and REJ homolog (sperm receptor for egg jelly homolog, sea urchin) antibody, polycystin (PKD) family receptor for egg jelly antibody, Pkdrej antibody, PKDREJ antibody

Background: PKDREJ is a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction.This intronless gene encodes a member of the polycystin protein family. The encoded protein contains 11 transmembrane domains, a receptor for egg jelly (REJ) domain, a G-protein-coupled receptor proteolytic site (GPS) domain, and a polycystin-1, lipoxygenase, alpha-toxin (PLAT) domain. This protein may play a role in human reproduction. Alternative splice variants have been described but their biological natures have not been determined.
Alias Symbols: -
Protein Interaction Partner: LNX2, LNX1,
Protein Size: 2253

Molecular Weight: 254 kDa

Gene ID: 10343

NCBI Accession: NM_006071, NP_006062

UniProt: Q9NTG1