Potassium Voltage-Gated Channel, Subfamily G, Member 4 (Kcng4) (N-Term) antibody

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Antigen
Synonyms si:dkey-246g23.3, KV6.3, KV6.4, 4921535I01Rik, AW049024
Epitope
N-Term
(3), (1), (1), (1), (1)
Reactivity
Human
(22), (18), (16)
Host
Rabbit
(24)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(13), (11), (10), (4), (4), (3)
Pubmed 1 reference available
Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human KCNG4
Sequence QEELAYWGIE EAHLERCCLR KLLRKLEELE ELAKLHREDV LRQQRETRRP
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against KCNG4. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name KCNG4 (Kcng4 Antibody Abstract)
Background Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. KCNG4 is a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The protein has strong expression in brain.Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily G. This member functions as a modulatory subunit. The gene has strong expression in brain. Multiple alternatively spliced variants have been found in normal and cancerous tissues.
Molecular Weight 59 kDa
Gene ID 93107
NCBI Accession NM_172347, NP_758857
UniProt Q8TDN1
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 519 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Potassium Voltage-Gated Channel, Subfamily G, Member 4 (Kcng4) (N-Term) antibody WB Suggested Anti-KCNG4 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Background publications Gutman, Chandy, Grissmer et al.: "International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels." in: Pharmacological reviews, Vol. 57, Issue 4, pp. 473-508, 2005 (PubMed).

Validation Images
Catalog No. ABIN404999
289.00 $
Plus shipping costs $45.00
Quantity
Price
50 μg
289.00 $

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