Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) antibody

Details for Product No. ABIN405190
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Antigen
Synonyms Mar7, BCUR1, Mart7, RGD1565644, Gm366, LDOC1
Epitope
N-Term
(3), (2), (1), (1)
Reactivity
Cow (Bovine), Human
(26), (12), (12), (3)
Host
Rabbit
(18), (8)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(10), (9), (8), (4), (3), (2), (1)
Pubmed 1 reference available
Catalog no. ABIN405190
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the N terminal of human LDOC1
Sequence MVDELVLLLHALLMRHRALSIENSQLMEQLRLLVCERASL LRQVRPPSCP
Predicted Reactivity Bovine : 100 %, Guinea pig : 100 %, Human : 100 %, Pig : 100 %, Rabbit : 100 %, Dog : 80 %
Characteristics This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name LDOC1
Background LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Molecular Weight 17 kDa
Gene ID 23641
NCBI Accession NM_012317, NP_036449
UniProt O95751
Research Area Cancer, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 146 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) antibody WB Suggested Anti-LDOC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:12500
Positive Control: HepG2 cell lysate
anti-Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) antibody (2) anti-Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1) (N-Term) antibody (Image 2)
Background publications Ross, Grafham, Coffey et al.: "The DNA sequence of the human X chromosome...." in: Nature, Vol. 434, Issue 7031, pp. 325-37, 2005 (PubMed).

Hosts (18), (8)
Reactivities (26), (12), (12), (3)
Applications (10), (9), (8), (4), (3), (2), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (3), (2), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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