LDOC1 antibody (N-Term)

Catalog No. ABIN405190

Product Details anti-LDOC1 Antibody

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Binding Specificity: N-Term

Reactivity: Human, Rat, Cow, Rabbit, Dog, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LDOC1 antibody is un-conjugated

Application: Immunohistochemistry (IHC), Western Blotting (WB)

Sequence: MVDELVLLLH ALLMRHRALS IENSQLMEQL RLLVCERASL LRQVRPPSCP

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Rabbit: 100%, Rat: 79%

Characteristics: This is a rabbit polyclonal antibody against LDOC1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human LDOC1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 146 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for LDOC1

Target: LDOC1 (Leucine Zipper, Down-Regulated in Cancer 1 (LDOC1))

Alternative Name: LDOC1 (LDOC1 Products)

Synonyms: BCUR1 antibody, Mar7 antibody, Mart7 antibody, RGD1565644 antibody, Gm366 antibody, LDOC1 antibody, LDOC1, regulator of NFKB signaling antibody, regulator of NFKB signaling antibody, LDOC1 antibody, Ldoc1 antibody

Background: LDOC1 contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.The protein encoded by this gene contains a leucine zipper-like motif and a proline-rich region that shares marked similarity with an SH3-binding domain. The protein localizes to the nucleus and is down-regulated in some cancer cell lines. It is thought to regulate the transcriptional response mediated by the nuclear factor kappa B (NF-kappaB). The gene has been proposed as a tumor suppressor gene whose protein product may have an important role in the development and/or progression of some cancers.
Alias Symbols: BCUR1, Mar7, Mart7
Protein Interaction Partner: LENG1, TTC23, MEAF6, SH2D4A, CTNNBL1, DPPA4, FAM90A1, C1orf109, FAM208B, TBC1D7, PRPF31, LDOC1, PEG10, NXF1, ZBTB24, HDAC4, ATP6V1G1, HGS, LATS1, RAB29, TNNT1, TMSB4XP1, SDCBP, DPF2, PSMA1, MFAP1, BARD1, ATF4, AES, ZNF774, ZNF564, HAUS1, ZGPAT, CCDC33, IN
Protein Size: 146

Molecular Weight: 17 kDa

Gene ID: 23641

NCBI Accession: NM_012317, NP_036449

UniProt: O95751