Homeobox Protein OTX1 (N-Term) antibody

Details for Product No. ABIN405197
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Antigen
Synonyms OTX1X, otx1-A, xotx1, A730044F23Rik, jv, cb769, fj99f05, otx1, wu:fj99f05, zOtx1
Epitope
N-Term
(9), (7), (5), (4), (3), (2), (2), (2), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Dog (Canine), Zebrafish (Danio rerio), Xenopus laevis, Cow (Bovine), Human
(43), (18), (17), (16), (16), (12), (2), (1), (1), (1), (1)
Host
Rabbit
(35), (9)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (16), (10), (4), (3), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN405197
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human OTX1
Sequence PRKQRRERTT FTRSQLDVLE ALFAKTRYPD IFMREEVALK INLPESRVQV
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Dog : 100 %, Guinea pig : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %
Characteristics This is a rabbit polyclonal antibody against OTX1. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name OTX1
Background OTX1 probably plays a role in the development of the brain and the sense organs. OTX1 can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
Molecular Weight 37 kDa
Gene ID 5013
NCBI Accession NP_055377, NM_014562
UniProt P32242
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 354 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Hillier, Graves, Fulton et al.: "Generation and annotation of the DNA sequences of human chromosomes 2 and 4. ..." in: Nature, Vol. 434, Issue 7034, pp. 724-31, 2005 (PubMed).

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