SRY (Sex Determining Region Y)-Box 17 (SOX17) (Middle Region) antibody

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Antigen
Synonyms sox17, Xsox17, sox17beta, sox17-beta, tSox17beta, Xsox17-beta, SOX17, Sox17alpha, Xsox17-alpha, Xsox17alpha, sox17-alpha, tSox17alpha, xSox17alpha1, xSox17alpha2, xsox17a, sox7/17, VUR3, Sox
Epitope
Middle Region
(25), (18), (8), (4), (4), (2), (1), (1), (1), (1)
Reactivity
Dog (Canine), Human, Mouse (Murine)
(69), (15), (8), (5), (3), (3), (3), (1), (1), (1)
Host
Rabbit
(30), (27), (20)
Clonality
Polyclonal
Conjugate
Un-conjugated
(3), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(45), (33), (17), (9), (8), (7), (6), (5), (3), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human SOX17
Blocking Peptide Blocking peptide for this product available: SRY (Sex Determining Region Y)-Box 17 (SOX17) (Middle Region) peptide (ABIN984262)
Sequence RTEFEQYLHF VCKPEMGLPY QGHDSGVNLP DSHGAISSVV SDASSAVYYC
Predicted Reactivity Human : 100 %, Guinea pig : 90 %, Dog : 80 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against SOX17. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SOX17 (SOX17 Antibody Abstract)
Background The SOX17 gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins.
Molecular Weight 44 kDa
Gene ID 64321
NCBI Accession NP_071899, NM_022454
UniProt Q9H6I2
Research Area Embryogenesis, Embryonic stem cells, Transcription Factors
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 414 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-SRY (Sex Determining Region Y)-Box 17 (SOX17) (Middle Region) antibody (ABIN405250) WB Suggested Anti-SOX17 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-SRY (Sex Determining Region Y)-Box 17 (SOX17) (Middle Region) antibody (ABIN405250) anti-SRY (Sex Determining Region Y)-Box 17 (SOX17) (Middle Region) antibody (Image 2)
Background publications Zhang, Glöckner, Guo et al.: "Epigenetic inactivation of the canonical Wnt antagonist SRY-box containing gene 17 in colorectal cancer." in: Cancer research, Vol. 68, Issue 8, pp. 2764-72, 2008 (PubMed).

Catalog No. ABIN405250
$289.00
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