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EXOSC2 antibody (Middle Region)

EXOSC2 Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN405355
  • Target See all EXOSC2 Antibodies
    EXOSC2 (Exosome Component 2 (EXOSC2))
    Binding Specificity
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 19
    • 7
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)
    Host
    • 13
    • 6
    Rabbit
    Clonality
    • 14
    • 5
    Polyclonal
    Conjugate
    • 19
    This EXOSC2 antibody is un-conjugated
    Application
    • 16
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    AEVQAVFSDG AVSLHTRSLK YGKLGQGVLV QVSPSLVKRQ KTHFHDLPCG
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    Characteristics
    This is a rabbit polyclonal antibody against EXOSC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human EXOSC2
    Top Product
    Discover our top product EXOSC2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 293 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • van Dijk, Schilders, Pruijn: "Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways." in: RNA (New York, N.Y.), Vol. 13, Issue 7, pp. 1027-35, (2007) (PubMed).

  • Target
    EXOSC2 (Exosome Component 2 (EXOSC2))
    Alternative Name
    EXOSC2 (EXOSC2 Products)
    Synonyms
    EXOSC2 antibody, exosc2 antibody, MGC97533 antibody, RRP4 antibody, Rrp4p antibody, hRrp4p antibody, p7 antibody, Rrp4 antibody, fa97b01 antibody, wu:fa97b01 antibody, zgc:110117 antibody, exosome component 2 antibody, exosome component 2 L homeolog antibody, EXOSC2 antibody, exosc2 antibody, Bm1_33895 antibody, PTRG_00114 antibody, Exosc2 antibody, exosc2.L antibody
    Background
    EXOSC2 belongs to the exosome, a RNA-processing complex, which is at least involved in the 3' processing of the 7S pre-rRNA to the mature 5.8S rRNA. It exhibits a 3'-5' exoribonuclease activity.
    Alias Symbols: RRP4, Rrp4p, hRrp4p, p7
    Protein Interaction Partner: GPX1, ST6GALNAC1, MRPL48, EXOSC7, RNF8, GALNT13, ZNF408, AICDA, METTL22, UBC, UPF1, MDC1, BARD1, EXOSC5, EXOSC4, EXOSC3, DEK, RAN, EXOSC9, DIS3L, DIS3, UBD, CAND1, HDGF, MEPCE, SKIV2L2, EXOSC6, KHSRP, MPP6, EXOSC8, UPF3A, UPF2,
    Protein Size: 293
    Molecular Weight
    32 kDa
    Gene ID
    23404
    NCBI Accession
    NM_014285, NP_055100
    UniProt
    Q13868
    Pathways
    SARS-CoV-2 Protein Interactome
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