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Nucleolar Protein 6 antibody (N-Term)

NOL6 Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN405371
  • Target See all Nucleolar Protein 6 (NOL6) Antibodies
    Nucleolar Protein 6 (NOL6)
    Binding Specificity
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 15
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit, Saccharomyces cerevisiae
    Host
    • 12
    • 3
    Rabbit
    Clonality
    • 15
    Polyclonal
    Conjugate
    • 11
    • 2
    • 1
    • 1
    This Nucleolar Protein 6 antibody is un-conjugated
    Application
    • 10
    • 5
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    SRKRTLAEPP AKGLLQPVKL SRAELYKEPT NEELNRLRET EILFHSSLLR
    Predicted Reactivity
    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Yeast: 90%
    Characteristics
    This is a rabbit polyclonal antibody against NOL6. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human NOL6
    Top Product
    Discover our top product NOL6 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 1146 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    Nucleolar Protein 6 (NOL6)
    Alternative Name
    NOL6 (NOL6 Products)
    Synonyms
    NRAP antibody, UTP22 antibody, bA311H10.1 antibody, nrap antibody, utp22 antibody, AA410091 antibody, Nrap antibody, nucleolar protein 6 antibody, nucleolar protein 6 L homeolog antibody, nucleolar protein family 6 (RNA-associated) antibody, NOL6 antibody, Nol6 antibody, nol6.L antibody
    Background
    NOL6 is a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. The nucleolus is a dense subnuclear membraneless organelle that assembles around clusters of rRNA genes and functions in ribosome biogenesis. This gene encodes a nucleolar RNA-associated protein that is highly conserved between species. RNase treatment of permeabilized cells indicates that the nucleolar localization is RNA dependent. Further studies suggest that the protein is associated with ribosome biogenesis through an interaction with pre-rRNA primary transcripts. Alternative splicing has been observed at this locus and two splice variants encoding distinct isoforms have been identified.
    Alias Symbols: FLJ21959, MGC14896, MGC14921, MGC20838, NRAP, UTP22, bA311H10.1
    Protein Interaction Partner: UBC, SIAH1, LIN28A, RNF2, BMI1, EED, SIRT7, SUMO2, SUMO1, G3BP1,
    Protein Size: 1146
    Molecular Weight
    127 kDa
    Gene ID
    65083
    NCBI Accession
    NM_022917, NP_075068
    UniProt
    Q9H6R4
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