serine/arginine-Rich Splicing Factor 8 (SRSF8) (Middle Region) antibody

Details for Product No. ABIN405374
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Antigen
Synonyms DSM-1, SFRS2B, SRP46
Epitope
Middle Region
(15), (14), (6), (1), (1), (1), (1), (1)
Reactivity
Human
(35), (1)
Host
Rabbit
(35)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB)
(33), (27), (3), (2), (1)
Pubmed 1 reference available
Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human SFRS2B
Sequence YRESRYGGSH YSSSGYSNSR YSRYHSSRSH SKSGSSTSSR SASTSKSSSA
Predicted Reactivity Human :100 %
Characteristics This is a rabbit polyclonal antibody against SFRS2B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SFRS2B (SRSF8 Antibody Abstract)
Background The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. SFRS2B is a member of the SR family and functions as an essential splicing factor in vitro.The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The protein encoded by this gene is a member of the SR family and functions as an essential splicing factor in vitro. This gene is thought to be an expressed PR264/SC35 retropseudogene.
Molecular Weight 32 kDa
Gene ID 10929
NCBI Accession NM_032102, NP_115285
UniProt Q9BRL6
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 282 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-serine/arginine-Rich Splicing Factor 8 (SRSF8) (Middle Region) antibody WB Suggested Anti-SFRS2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
anti-serine/arginine-Rich Splicing Factor 8 (SRSF8) (Middle Region) antibody (2) WB Suggested Anti-SFRS2B
Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 ...
Background publications Li, Hawkins, Harvey et al.: "Regulation of alternative splicing by SRrp86 and its interacting proteins." in: Molecular and cellular biology, Vol. 23, Issue 21, pp. 7437-47, 2003 (PubMed).

Validation Images
Catalog No. ABIN405374
289.00 $
Plus shipping costs $45.00
Quantity
Price
50 μg
289.00 $

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