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serine/arginine-Rich Splicing Factor 8 (SRSF8) (Middle Region) antibody

Details for Product No. ABIN405374
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Antigen
Synonyms DSM-1, SFRS2B, SRP46
Epitope
Middle Region
(7), (6), (6), (1), (1), (1)
Reactivity
Human
(21)
Host
Rabbit
(22)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(22), (17), (1)
Pubmed 1 reference available
Quantity 50 µg
Options
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Availability Will be delivered in 2 to 3 Business Days
Catalog No. ABIN405374
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide directed towards the middle region of human SFRS2B
Sequence YRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSR SASTSKSSSA
Predicted Reactivity Human :100 %
Characteristics This is a rabbit polyclonal antibody against SFRS2B. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name SFRS2B
Background The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. SFRS2B is a member of the SR family and functions as an essential splicing factor in vitro.The SR (serine/arginine-rich) family contains a number of phosphoproteins that function as essential and alternative splicing factors. The SR family of proteins is characterized by the presence of a ribonucleoprotein (RNP)-type RNA binding motif and a carboxyl-terminal arginine-serine-rich (RS) domain. The protein encoded by this gene is a member of the SR family and functions as an essential splicing factor in vitro. This gene is thought to be an expressed PR264/SC35 retropseudogene.
Molecular Weight 32 kDa
Gene ID 10929
NCBI Accession NM_032102, NP_115285
UniProt Q9BRL6
Research Area Chromatin and Nuclear Signaling, DNA/RNA
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 282 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-serine/arginine-Rich Splicing Factor 8 (SRSF8) (Middle Region) antibody WB Suggested Anti-SFRS2B Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: 721_B cell lysate
Background publications Li, Hawkins, Harvey et al.: "Regulation of alternative splicing by SRrp86 and its interacting proteins." in: Molecular and cellular biology, Vol. 23, Issue 21, pp. 7437-47, 2003 (PubMed).

Hosts (22)
Reactivities (21)
Applications (22), (17), (1)
Conjugates (1), (1), (1), (1), (1), (1)
Epitopes (7), (6), (6), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN405374
289.00 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
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