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FBLN3 antibody (Middle Region)

FBLN3 Reactivity: Human, Mouse, Rat, Rabbit, Pig, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio) WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN405398
  • Target See all FBLN3 Antibodies
    FBLN3 (Fibulin 3 (FBLN3))
    Binding Specificity
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 52
    • 24
    • 15
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Rabbit, Pig, Cow, Dog, Guinea Pig, Horse, Zebrafish (Danio rerio)
    Host
    • 47
    • 6
    Rabbit
    Clonality
    • 48
    • 5
    Polyclonal
    Conjugate
    • 35
    • 6
    • 5
    • 3
    • 2
    • 2
    This FBLN3 antibody is un-conjugated
    Application
    • 48
    • 33
    • 27
    • 11
    • 10
    • 8
    • 8
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    KYMSIRSDRS VPSDIFQIQA TTIYANTINT FRIKSGNENG EFYLRQTSPV
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Guinea Pig: 86%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 92%
    Characteristics
    This is a rabbit polyclonal antibody against EFEMP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human EFEMP1
    Top Product
    Discover our top product FBLN3 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 493 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Lutter, Xie, Tatin, Makinen: "Smooth muscle-endothelial cell communication activates Reelin signaling and regulates lymphatic vessel formation." in: The Journal of cell biology, Vol. 197, Issue 6, pp. 837-49, (2012) (PubMed).

  • Target
    FBLN3 (Fibulin 3 (FBLN3))
    Alternative Name
    EFEMP1 (FBLN3 Products)
    Synonyms
    DHRD antibody, DRAD antibody, FBLN3 antibody, FBNL antibody, FIBL-3 antibody, MLVT antibody, MTLV antibody, S1-5 antibody, T16 antibody, EGF containing fibulin like extracellular matrix protein 1 antibody, EGF-containing fibulin-like extracellular matrix protein 1 antibody, epidermal growth factor-containing fibulin-like extracellular matrix protein 1 antibody, EFEMP1 antibody, Efemp1 antibody
    Background
    EFEMP1 gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.This gene spans approximately 18 kb of genomic DNA and consists of 12 exons. Alternative splice patterns in the 5' UTR result in three transcript variants encoding the same extracellular matrix protein. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy.
    Alias Symbols: DHRD, DRAD, FBLN3, FBNL, FLJ35535, MGC111353, MLVT, MTLV, S1-5
    Protein Interaction Partner: TXNDC5, RIC8A, BAG6, TRAF2, SGTA, env, HCVgp1, KHDRBS1, TNIP1, SOCS6, UBC, PDIA3, NOS3, GFI1B, ATN1, RERE, ATXN7, CACNA1A, ARAF, TIMP3, RAF1,
    Protein Size: 493
    Molecular Weight
    53 kDa
    Gene ID
    2202
    NCBI Accession
    NM_004105, NP_004096
    UniProt
    Q12805
    Pathways
    EGFR Signaling Pathway
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