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Details for Product No. ABIN405419

Transglutaminase 1, Keratinocyte (TGM1) (N-Term) antibody

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Antigen
Synonyms ARCI1, ICR2, KTG, LI, LI1, TGASE, TGK, 2310004J08Rik, Tgase1, TGM1, fa12g12, wu:fa12g12, zgc:112355
Epitope
»Alternatives N-Term
Reactivity
»Alternatives Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN405419
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-TGM1 antibody: synthetic peptide directed towards the N terminal of human TGM1
Sequence RGSSSGTRRPGSRGSDSRRPVSRGSGVNAAGDGTIREGML VVNGVDLLSS
Predicted Reactivity Guinea pig : 100%, Human : 100%, Mouse : 100%, Pig : 100%, Rat : 100%, Bovine : 92%, Dog : 92%, Rabbit : 92%
Characteristics This is a rabbit polyclonal antibody against TGM1. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name TGM1
Background TGM1 is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).The protein encoded by this gene is a membrane protein that catalyzes the addition of an alkyl group from an akylamine to a glutamine residue of a protein, forming an alkylglutamine in the protein. This protein alkylation leads to crosslinking of proteins and catenation of polyamines to proteins. This gene contains either one or two copies of a 22 nt repeat unit in its 3' UTR. Mutations in this gene have been associated with autosomal recessive lamellar ichthyosis (LI) and nonbullous congenital ichthyosiform erythroderma (NCIE).
Molecular Weight 90kDa
Gene ID 7051
NCBI Accession NP_000350, NM_000359
UniProt P22735
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-TGM1 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Marietta, Camilleri, Castro et al.: "Transglutaminase autoantibodies in dermatitis herpetiformis and celiac sprue." in: The Journal of investigative dermatology, Vol. 128, Issue 2, pp. 332-5, 2008 (PubMed).

Alternatives for antigen "Transglutaminase 1, Keratinocyte (TGM1)", type "Antibodies"
Hosts (25), (5), (2)
Reactivities (29), (7), (7), (1), (1), (1), (1)
Applications (29), (14), (7), (6), (4), (3), (2), (2), (1)
Conjugates (1), (1), (1)
Epitopes (3), (1)
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