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SLC5A5 antibody (Middle Region)

SLC5A5 Reactivity: Human WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN405589
  • Target See all SLC5A5 Antibodies
    SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
    Binding Specificity
    • 46
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 72
    • 33
    • 30
    • 2
    • 2
    • 2
    Human
    Host
    • 52
    • 21
    Rabbit
    Clonality
    • 50
    • 21
    Polyclonal
    Conjugate
    • 26
    • 5
    • 5
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC5A5 antibody is un-conjugated
    Application
    • 63
    • 56
    • 22
    • 18
    • 13
    • 11
    • 9
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    PSEQTMRVLP SSAARCVALS VNASGLLDPA LLPANDSSRA PSSGMDASRP
    Predicted Reactivity
    Human: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SLC5A5. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SLC5A5
    Top Product
    Discover our top product SLC5A5 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 643 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Liu, Lunsford, Tong, Ashitate, Gibbs, Yu, Choi, Henske, Frangioni: "Real-time monitoring of tumorigenesis, dissemination, & drug response in a preclinical model of lymphangioleiomyomatosis/tuberous sclerosis complex." in: PLoS ONE, Vol. 7, Issue 6, pp. e38589, (2012) (PubMed).

  • Target
    SLC5A5 (Solute Carrier Family 5 (Sodium/iodide Cotransporter), Member 5 (SLC5A5))
    Alternative Name
    SLC5A5 (SLC5A5 Products)
    Synonyms
    Na(+)/I(-) cotransporter antibody, Na(+)/I(-) symporter antibody, Nis antibody, solute carrier family 5 member 5 antibody, Slc5a5 antibody
    Background
    The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.The sodium-iodide symporter (NIS, or SLC5A5) is a key plasma membrane protein that mediates active I- uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated I- uptake is the first step in the biosynthesis of iodine-containing thyroid hormones (Dohan et al., 2007 [PubMed 18077370]).[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
    Alias Symbols: NIS, TDH1
    Protein Interaction Partner: ERBB2IP, SLC5A5,
    Protein Size: 643
    Molecular Weight
    69 kDa
    Gene ID
    6528
    NCBI Accession
    NM_000453, NP_000444
    UniProt
    Q92911
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