AWAT2 antibody (C-Term)

Catalog No. ABIN405651

Product Details anti-AWAT2 Antibody

Target: AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Horse, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AWAT2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: GEPLPMPKIE NPSQEIVAKY HTLYIDALRK LFDQHKTKFG ISETQELEII

Predicted Reactivity: Dog: 86%, Guinea Pig: 86%, Horse: 79%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against DGAT2L4. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DGAT2L4

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 333 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AWAT2

Target: AWAT2 (Acyl-CoA Wax Alcohol Acyltransferase 2 (AWAT2))

Alternative Name: DGAT2L4 (AWAT2 Products)

Synonyms: DGAT2L4 antibody, ARAT antibody, DC4 antibody, MFAT antibody, WS antibody, 9430062J17Rik antibody, Dgat2l4 antibody, RGD1565111 antibody, acyl-CoA wax alcohol acyltransferase 2 antibody, AWAT2 antibody, Awat2 antibody

Background: DGAT2L4 is acyltransferase that predominantly esterify long chain (wax) alcohols with acyl-CoA-derived fatty acids to produce wax esters. Wax esters are enriched in sebum, suggesting that it plays a central role in lipid metabolism in skin. It has no activity using decyl alcohol and significantly prefers the C16 and C18 alcohols. DGAT2L4 may also have 2-acylglycerol O-acyltransferase (MGAT) and acyl-CoA:retinol acyltransferase (ARAT) activities, to catalyze the synthesis of diacylglycerols and retinyl esters, however this activity is unclear in vivo.
Alias Symbols: AWAT2, DC4, MFAT, WS, DGAT2L4
Protein Size: 333

Molecular Weight: 38 kDa

Gene ID: 158835

NCBI Accession: NM_001002254, NP_001002254

UniProt: Q6E213