Ubiquinol-Cytochrome C Reductase, Complex III Subunit X (UQCR10) (Middle Region) antibody

Details for Product No. ABIN405656
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Antigen
Synonyms Ucrc, UCRC, qcr9, ucrc, HSPC051, HSPC151, QCR9, UCCR7.2, 1110020P15Rik, AA960494
Epitope
Middle Region
(2), (1)
Reactivity
Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Pig (Porcine), Xenopus laevis, Human, Chicken
(5), (1), (1)
Host
Rabbit
(4), (1)
Clonality
Polyclonal
Application
Western Blotting (WB)
(3), (2)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN405656
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human UCRC
Sequence LFRRTSTFAL TIIVGVMFFE RAFDQGADAI YDHINEGKLW KHIKHKYENK
Predicted Reactivity Rat :100 %,   Human :100 %,   Mouse :90 %,   Bovine :90 %,   Dog :80 %,   Pig :80 %,   African clawed frog :80 %,   Western clawed frog :80 %,   Chicken :70 %,  
Characteristics This is a rabbit polyclonal antibody against UCRC. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name UCRC
Background UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane.UCRC is a subunit of mitochondrial complex III (ubiquinol-cytochrome c reductase, EC 1.10.2.2), which forms the middle segment of the respiratory chain of the inner mitochondrial membrane (Schagger et al., 1995 [PubMed 8592474]).
Molecular Weight 7 kDa
Gene ID 29796
NCBI Accession NM_013387, NP_037519
UniProt Q9UDW1
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 63 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Ubiquinol-Cytochrome C Reductase, Complex III Subunit X (UQCR10) (Middle Region) antibody WB Suggested Anti-UCRC Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: MCF7 cell lysate
Background publications Guzy, Hoyos, Robin et al.: "Mitochondrial complex III is required for hypoxia-induced ROS production and cellular oxygen sensing." in: Cell metabolism, Vol. 1, Issue 6, pp. 401-8, 2005 (PubMed).

Validation Images
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