anti-Podoplanin antibody (PDPN) (Middle Region)

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Antigen
Synonyms PDPN, AGGRUS, GP36, GP40, Gp38, HT1A-1, OTS8, PA2.26, T1A, T1A-2, OTS-8, RANDAM-2, T1-alpha, T1a, T1alpha, E11, RTI40
Epitope
Middle Region
(42), (17), (17), (14), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(189), (69), (15), (3)
Host
Rabbit
(101), (68), (29), (26), (17), (14), (2)
Clonality
Polyclonal
Conjugate
This Podoplanin antibody is un-conjugated
(16), (12), (9), (9), (6), (6), (5), (5), (3), (2), (2), (1)
Application
Western Blotting (WB)
(146), (75), (74), (65), (40), (34), (30), (14), (5), (5), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human PDPN
Blocking Peptide Blocking peptide for this product available: Podoplanin (PDPN) (Middle Region) peptide (ABIN981554)
Sequence VATSHSTEKV DGDTQTTVEK DGLSTVTLVG IIVGVLLAIG FIGAIIVVVM
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against PDPN. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PDPN (PDPN Antibody Abstract)
Background PDPN is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
Molecular Weight 25 kDa
Gene ID 10630
NCBI Accession NP_006465, NM_006474
Research Area Cancer
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 238 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Podoplanin antibody (PDPN) (Middle Region) (ABIN405667) WB Suggested Anti-PDPN Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Christou, Pearce, Watson et al.: "Renal cells activate the platelet receptor CLEC-2 through podoplanin." in: The Biochemical journal, Vol. 411, Issue 1, pp. 133-40, 2008 (PubMed).

Catalog No. ABIN405667
$289.00
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