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Details for Product No. ABIN405667

Podoplanin (PDPN) (Middle Region) antibody

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Antigen
Synonyms T1A, GP36, GP40, Gp38, OTS8, T1A-2, AGGRUS, HT1A-1, PA2.26, OTS-8, RANDAM-2, T1-alpha, T1a, T1alpha, E11, RTI40, PDPN
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN405667
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-PDPN antibody: synthetic peptide directed towards the middle region of human PDPN
Sequence VATSHSTEKVDGDTQTTVEKDGLSTVTLVGIIVGVLLAIG FIGAIIVVVM
Predicted Reactivity Human : 100%
Characteristics This is a rabbit polyclonal antibody against PDPN. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name PDPN
Background PDPN is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.This gene encodes a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor. The specific function of this protein has not been determined but it has been proposed as a marker of lung injury. Alternatively spliced transcript variants encoding different isoforms have been identified.
Molecular Weight 25kDa
Gene ID 10630
NCBI Accession NP_006465, NM_006474
UniProt Q86YL7-3
Research Area Cancer
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-PDPN antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Christou, Pearce, Watson et al.: "Renal cells activate the platelet receptor CLEC-2 through podoplanin." in: The Biochemical journal, Vol. 411, Issue 1, pp. 133-40, 2008 (PubMed).

Alternatives for antigen "Podoplanin (PDPN)", type "Antibodies"
Hosts (66), (54), (15), (13), (5), (4), (1)
Reactivities (111), (43), (19), (2)
Applications (92), (51), (44), (35), (34), (28), (21), (20), (15), (11), (6), (3), (1), (1)
Conjugates (9), (5), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1)
Epitopes (12), (7), (6), (6), (3), (1), (1)
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