Dystrobrevin beta antibody (C-Term)
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- Target See all Dystrobrevin beta (DTNB) Antibodies
- Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))
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Binding Specificity
- C-Term
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Reactivity
- Human, Rat, Mouse, Dog, Horse, Rabbit, Cow, Guinea Pig, Zebrafish (Danio rerio)
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This Dystrobrevin beta antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- ASQPTPEKAQ QNPTLLAELR LLRQRKDELE QRMSALQESR RELMVQLEEL
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against DTNB. It was validated on Western Blot using a cell lysate as a positive control.
- Purification
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C terminal region of human DTNB
- Top Product
- Discover our top product DTNB Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 567 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- Dystrobrevin beta (DTNB) (Dystrobrevin, beta (DTNB))
- Alternative Name
- DTNB (DTNB Products)
- Synonyms
- DTNB antibody, bdtn antibody, btnb antibody, dtnb antibody, GDTN antibody, dtng antibody, gtnb antibody, wu:fc61h11 antibody, dystrobrevin beta antibody, dystrobrevin, beta b antibody, dystrobrevin, beta antibody, dystrobrevin, beta a antibody, DTNB antibody, dtnbb antibody, Dtnb antibody, dtnba antibody, dtnb antibody
- Background
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DTNB is dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin.This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alias Symbols: MGC17163, MGC57126
Protein Interaction Partner: CEP55, ABI3, GGA1, NUP62, MTUS2, HMG20A, ABI2, PPFIA1, VCP, TRAF2, KRT31, DTNB, DMD, ZBTB9, TXLNA, KRT40, SPZ1, DTNBP1, USHBP1, NDEL1, CEP63, MLC1, UBC, PRTFDC1, SNTG2, SNTG1, CCDC85B, TSACC, KIF5A, BEGAIN, PPFIBP2, UTRN, SNTA1, KIF5B,
Protein Size: 567 - Molecular Weight
- 64 kDa
- Gene ID
- 1838
- NCBI Accession
- NM_033148, NP_149160
- UniProt
- O60941
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