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Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ) (N-Term) antibody

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Antigen
Synonyms GPI1, c407A10.1, Gpi1, Gpi1h, Gpi1p, Gpih
Epitope
N-Term
(7), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Rat (Rattus)
(12)
Host
Rabbit
(8), (4)
Clonality
Polyclonal
Application
Western Blotting (WB)
(12), (5), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human PIGQ
Blocking Peptide Blocking peptide for this product available: ABIN981748
Sequence PTVLPDRQAG ATTASTGGLA AVFDTVARSE VLFRSDRFDE GPVRLSHWQS
Predicted Reactivity Human : 100 %, Bovine : 90 %, Horse : 90 %, Rabbit : 90 %, Dog : 80 %, Rat : 80 %, Guinea pig : 70 %, Mouse : 70 %, Pig : 70 %
Characteristics This is a rabbit polyclonal antibody against PIGQ. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name PIGQ (PIGQ Antibody Abstract)
Background PIGQ is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. PIGQ is a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI).
Molecular Weight 65 kDa
Gene ID 9091
NCBI Accession NP_004195, NM_004204
UniProt B2RAU6
Research Area Signaling, Fatty Acids
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 581 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Phosphatidylinositol Glycan Anchor Biosynthesis, Class Q (PIGQ) (N-Term) antibody (ABIN405821) WB Suggested Anti-PIGQ Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Martin, Han, Gordon et al.: "The sequence and analysis of duplication-rich human chromosome 16. ..." in: Nature, Vol. 432, Issue 7020, pp. 988-94, 2004 (PubMed).

Catalog No. ABIN405821
$289.00
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