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Details for Product No. ABIN405948

DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L) (Middle Region) antibody

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Antigen
Synonyms DOT1, KMT4, Dot1, mDot1, AW907654, A630076O07, NV11307, DOT1L
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Rat (Rattus), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN405948
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
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Availability Will be delivered in 2 to 3 Business Days
Predicted Reactivity Human :100%,   Rat :85%,  
Characteristics This is a rabbit polyclonal antibody against DOT1L. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name DOT1L
Background DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.
Molecular Weight 165kDa
Gene ID 27185
NCBI Accession NP_115871, NM_032482
UniProt Q8TEK3
Research Area Neurology, Alzheimer's Disease
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Steger, Lefterova, Ying et al.: "DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells." in: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2825-39, 2008 (PubMed).

Alternatives for antigen "DOT1-Like, Histone H3 Methyltransferase (S. Cerevisiae) (DOT1L)", type "Antibodies"
Hosts (8), (5), (3)
Reactivities (15), (1)
Applications (10), (6), (5), (3), (2), (2), (1), (1)
Epitopes (3), (2), (1), (1), (1)
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