Disrupted in Schizophrenia 1 (DISC1) antibody
| Antigen |
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| Synonyms |
SCZD9, C1orf136, FLJ13381, FLJ21640, FLJ25311, FLJ41105, KIAA0457, DISC1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN405948 |
| Quantity |
50 µg (Variants) |
| Price |
317.90 $ Plus shipping costs $45.00
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Bulk discount
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| Shipping to |
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| Availability |
Will be delivered in 2 to 3 Business Days |
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Alternative name
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DISC1
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Gene ID
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DISC1
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UniProt
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Q8TEK3
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Immunogen
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The immunogen for anti-DISC1 antibody: synthetic peptide directed towards the middle region of human DISC1
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Sequence
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LAGRKPAPAGEPVNSSKWKSTFSPISDIGLAKSADSPLQA SSALSQNSLF
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Cross-Reactivity
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Human, Rat (Rattus)
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Format
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Lyophilized
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Reconstitution
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Add 50 µl of distilled water. Final anti-DISC1 antibody concentration is 1 mg/ml.
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Description
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DOT1L is a histone methyltransferase. It methylates 'Lys-79' of histone H3. Nucleosomes are preferred as substrate compared to free histones.
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Characteristics
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Antigen Size: 1537 amino acids
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Molecular Weight
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165kDa
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Application Notes
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WB Suggested Anti-DISC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Hela cell lysate.
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Purification
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Affinity Purified
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Buffer
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PBS
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Storage (Long Term)
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For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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Storage (Short Term)
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Any unfrozen and/or unused material can be stored at 4°C for short term use (< 1 week), and should not be re-frozen.
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Research Area
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Neurology, Alzheimer's Disease
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Restrictions
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For Research Use only
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Product
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Steger, Lefterova, Ying et al.: "DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells." in: Molecular and cellular biology, Vol. 28, Issue 8, pp. 2825-39, 2008 (PubMed).
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Alternatives for antigen "Disrupted in Schizophrenia 1 (DISC1)", type "Antibodies"
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Hosts
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Rabbit (40), Goat (4), Mouse (3)
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Reactivities
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Human (38), Mouse (Murine) (16), Rat (Rattus) (3), Cow (Bovine) (2), Cat (Feline) (1), Chicken (1), Dog (Canine) (1), Pig (Porcine) (1), Rabbit (1)
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Applications
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Western Blotting (WB) (43), ELISA (27), Immunohistochemistry (IHC) (10), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (9), Immunocytochemistry (ICC) (4), Immunofluorescence (IF) (4), Immunoprecipitation (IP) (2), Flow Cytometry (FACS) (1)
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Epitopes
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N-Term (9), C-Term (7), Internal Region (3), Middle Region (1)
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Alternatives 
2013 BioMed Central Research Awards
