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GMP Synthase antibody (Guanine Monphosphate Synthetase) (Middle Region)

Details for Product anti-GMPS Antibody No. ABIN406001, Supplier: Login to see New
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Antigen
Synonyms GMPS, AA591640, AI047208, sb:cb632, wu:fb76b01, wu:fi05a09, zgc:66002
Epitope
Middle Region
(6), (5), (5), (4), (4), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Cow (Bovine), Human, Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio)
(61), (23), (22), (1)
Host
Rabbit
(48), (14)
Clonality
Polyclonal
Conjugate
This GMP Synthase antibody is un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(47), (19), (14), (11), (10), (8), (3), (2)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human GMPS
Blocking Peptide Blocking peptide for this product available: ABIN977506
Sequence VCTALLNRAL NQEQVIAVHI DNGFMRKRES QSVEEALKKL GIQVKVINAA
Predicted Reactivity Chicken : 100 %, Dog : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Bovine : 90 %, Guinea pig : 90 %, Zebrafish : 90 %
Characteristics This is a rabbit polyclonal antibody against GMPS. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name GMPS (GMPS Antibody Abstract)
Background In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.In the de novo synthesis of purine nucleotides, IMP is the branch point metabolite at which point the pathway diverges to the synthesis of either guanine or adenine nucleotides. In the guanine nucleotide pathway, there are 2 enzymes involved in converting IMP to GMP, namely IMP dehydrogenase (IMPD1), which catalyzes the oxidation of IMP to XMP, and GMP synthetase, which catalyzes the amination of XMP to GMP.
Molecular Weight 77 kDa
Gene ID 8833
NCBI Accession NP_003866, NM_003875
UniProt P49915
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 693 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-GMP Synthase antibody (Guanine Monphosphate Synthetase) (Middle Region) (ABIN406001) WB Suggested Anti-GMPS Antibody Titration: 0.2-1 ug/ml
ELISA Titer: ...
Background publications Guo, Han, Adam et al.: "Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress." in: Biochemical and biophysical research communications, Vol. 337, Issue 4, pp. 1308-18, 2005 (PubMed).

Catalog No. ABIN406001
$289.00
Plus shipping costs $45.00

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