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SPTLC2 antibody (N-Term)

SPTLC2 Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN406006
  • Target See all SPTLC2 Antibodies
    SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
    Binding Specificity
    • 11
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    • 56
    • 35
    • 25
    • 7
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat, Cow, Dog, Guinea Pig, Rabbit, Zebrafish (Danio rerio), Horse
    Host
    • 56
    • 1
    Rabbit
    Clonality
    • 57
    Polyclonal
    Conjugate
    • 19
    • 6
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SPTLC2 antibody is un-conjugated
    Application
    • 53
    • 27
    • 13
    • 7
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Sequence
    VLTYVGYGVL TLFGYLRDFL RYWRIEKCHH ATEREEQKDF VSLYQDFENF
    Predicted Reactivity
    Cow: 100%, Dog: 91%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SPTLC2. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the N terminal region of human SPTLC2
    Top Product
    Discover our top product SPTLC2 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 562 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SPTLC2 (serine Palmitoyltransferase, Long Chain Base Subunit 2 (SPTLC2))
    Alternative Name
    SPTLC2 (SPTLC2 Products)
    Synonyms
    HSN1C antibody, LCB2 antibody, LCB2A antibody, NSAN1C antibody, SPT2 antibody, hLCB2a antibody, sptlc2 antibody, zgc:110661 antibody, AI173915 antibody, mKIAA0526 antibody, Pomt2 antibody, LCB2a antibody, SPTLC2 antibody, serine palmitoyltransferase long chain base subunit 2 antibody, serine palmitoyltransferase 2 antibody, serine palmitoyltransferase, long chain base subunit 2 S homeolog antibody, serine palmitoyltransferase, long chain base subunit 2a antibody, serine palmitoyltransferase, long chain base subunit 2 antibody, SPTLC2 antibody, LOC100446763 antibody, sptlc2 antibody, sptlc2.S antibody, sptlc2a antibody, Sptlc2 antibody
    Background
    SPTLC2 is a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. Alternatively spliced variants encoding different isoforms have been identified. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
    Alias Symbols: KIAA0526, LCB2, SPT2, HSN1C, LCB2A, NSAN1C, hLCB2a
    Protein Interaction Partner: UBC, BCL6, SPTLC1,
    Protein Size: 562
    Molecular Weight
    63 kDa
    Gene ID
    9517
    NCBI Accession
    NM_004863, NP_004854
    UniProt
    O15270
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