Cytidine Monophosphate N-Acetylneuraminic Acid Synthetase (CMAS) (N-Term) antibody

Details for Product No. ABIN406019
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Antigen
Synonyms CMAS, MGC126990, CSS, cmas, cmas1, si:dkey-183c2.1, wu:fj16c12, zgc:136241, AW208911, CMPNeu5Ac, D6Bwg0250e
Epitope
N-Term
(3), (2), (2), (2), (1), (1), (1)
Reactivity
Mouse (Murine), Rat (Rattus), Zebrafish (Danio rerio), Cow (Bovine), Dog (Canine), Human
(11), (2), (1)
Host
Rabbit
(7), (5)
Clonality
Polyclonal
Application
Western Blotting (WB)
(12), (5), (4), (2), (2)
Pubmed 1 reference available
Quantity 50 µg
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Catalog No. ABIN406019
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human CMAS
Sequence GRGVEKPPHL AALILARGGS KGIPLKNIKH LAGVPLIGWV LRAALDSGAF
Predicted Reactivity Bovine : 100 %, Chicken : 100 %, Dog : 100 %, Human : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %, Horse : 90 %
Characteristics This is a rabbit polyclonal antibody against CMAS. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name CMAS
Background CMAS is an enzyme that catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.The enzyme encoded by this gene catalyzes the activation of Neu5Ac to Cytidine 5-prime-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), which provides the substrate required for the addition of sialic acid. Sialic acids of cell surface glycoproteins and glycolipids play a pivotal role in the structure and function of animal tissues. The pattern of cell surface sialylation is highly regulated during embryonic development, and changes with stages of differentiation. Studies of a similar murine protein suggest that this protein localizes to the nucleus.
Molecular Weight 48 kDa
Gene ID 55907
NCBI Accession NP_061156, NM_018686
UniProt Q8NFW8
Research Area Signaling, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 434 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Background publications Kutsenko, Gizatullin, Al-Amin et al.: "NotI flanking sequences: a tool for gene discovery and verification of the human genome." in: Nucleic acids research, Vol. 30, Issue 14, pp. 3163-70, 2002 (PubMed).

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