Glucose Dehydrogenase (N-Term) antibody

Details for Product No. ABIN406155
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Antigen
Synonyms CG1152, Dmel\\CG1152, GDH, GLD, Go, gld, glucose dehydrogenase, l(3)84Cg, CORTRD1, G6PDH, AI785303, G6pd1, Gpd-1, Gpd1, H6pdh
Epitope
N-Term
(4), (1), (1), (1)
Reactivity
Rabbit, Mouse (Murine), Rat (Rattus), Cow (Bovine), Human
(15), (12), (3), (3), (1)
Host
Rabbit
(13), (8), (7)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (2)
Application
Western Blotting (WB)
(23), (16), (8), (6), (6), (5), (4), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN406155
289.00 $
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Immunogen Synthetic peptide directed towards the N terminal of human H6PD
Sequence HFSAQQLATE LGTFFQEEEM YRVDHYLGKQ AVAQILPFRD QNRKALDGLW
Predicted Reactivity Dog : 100 %, Guinea pig : 100 %, Mouse : 100 %, Rat : 100 %, Bovine : 90 %, Horse : 90 %
Characteristics This is a rabbit polyclonal antibody against H6PD. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name H6PD
Background There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.There are 2 forms of glucose-6-phosphate dehydrogenase. G form is X-linked and H form, encoded by this gene, is autosomally linked. This H form shows activity with other hexose-6-phosphates, especially galactose-6-phosphate, whereas the G form is specific for glucose-6-phosphate. Both forms are present in most tissues, but H form is not found in red cells.
Molecular Weight 89 kDa
Gene ID 9563
NCBI Accession NM_004285, NP_004276
UniProt O95479
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 791 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Glucose Dehydrogenase (N-Term) antibody WB Suggested Anti-H6PD Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: 721_B cell lysate
anti-Glucose Dehydrogenase (N-Term) antibody (2) Rabbit Anti-H6PD Antibody ,Paraffin Embedded Tissue: Human Lung Tissue
Primary Antibody Concentration: 1:100 Other Working Concentrations: 1/600
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:000
Magnification: 00X
Exposure Time: 0.5 - 2.0 sec
Background publications Smit, Dekker, de Jong et al.: "Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia." in: The Journal of clinical endocrinology and metabolism, Vol. 92, Issue 1, pp. 359-62, 2007 (PubMed).

Validation Images
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