ASB8 antibody (N-Term)

Catalog No. ABIN406214

Product Details anti-ASB8 Antibody

Target: ASB8 (Ankyrin Repeat and SOCS Box Containing 8 (ASB8))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ASB8 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSSSMWYIMQ SIQSKYSLSE RLIRTIAAIR SFPHDNVEDL IRGGADVNCT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against ASB8. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human ASB8

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 288 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for ASB8

Target: ASB8 (Ankyrin Repeat and SOCS Box Containing 8 (ASB8))

Alternative Name: ASB8 (ASB8 Products)

Synonyms: wu:fd16d08 antibody, zgc:64033 antibody, 4930539L19Rik antibody, AI788835 antibody, C430011H06Rik antibody, ankyrin repeat and SOCS box containing 8 antibody, ankyrin repeat and SOCS box-containing 8 antibody, ASB8 antibody, asb8 antibody, Asb8 antibody

Background: ASB8 may be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins.
Alias Symbols: FLJ21255, MGC5540, PP14212
Protein Interaction Partner: NEDD8, SLC25A6, PCNA, ZC3H6, HIF1AN, AMBRA1, KIF26B, TMED10, TUBB3, SLC25A13, CUL5, TCEB2, TCEB1, SERTAD1, RCN1, MCM7, HOXD4,
Protein Size: 288

Molecular Weight: 32 kDa

Gene ID: 140461

NCBI Accession: NM_024095, NP_077000

UniProt: Q9H765