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Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads) (Middle Region) antibody

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Antigen
Synonyms SCAD, acad3, scad, ACADS, ACAD3, Scad, wu:fc44c01, zgc:92400, AI196007, Bcd-1, Bcd1, Hdlq8
Epitope
Middle Region
(4), (4), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Chicken, Human, Mouse (Murine), Rat (Rattus), Xenopus laevis, Zebrafish (Danio rerio)
(45), (19), (16), (2), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(42), (6)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1)
Application
Western Blotting (WB)
(45), (18), (10), (7), (4), (2), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the middle region of human ACADS
Blocking Peptide Blocking peptide for this product available: ABIN972782
Sequence FTSGDKIGCF ALSEPGNGSD AGAASTTARA EGDSWVLNGT KAWITNAWEA
Predicted Reactivity African clawed frog : 100 %, Chicken : 100 %, Guinea pig : 100 %, Horse : 100 %, Human : 100 %, Mouse : 100 %, Rabbit : 100 %, Rat : 100 %, Zebrafish : 100 %, Bovine : 90 %, Pig : 90 %
Characteristics This is a rabbit polyclonal antibody against ACADS. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ACADS (Acads Antibody Abstract)
Background ACADS is a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency. This gene encodes a a tetrameric mitochondrial flavoprotein, which is a member of the acyl-CoA dehydrogenase family. This enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Mutations in this gene have been associated with Short Chain Acyl-CoA Dehydrogenase Deficiency.
Molecular Weight 42 kDa
Gene ID 35
NCBI Accession NP_000008, NM_000017
UniProt P16219
Research Area Cancer, Fatty Acids, Metabolism
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 412 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-Acyl-CoA Dehydrogenase, C-2 To C-3 Short Chain (Acads) (Middle Region) antibody (ABIN406378) WB Suggested Anti-ACADS Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: Tein, Elpeleg, Ben-Zeev et al.: "Short-chain acyl-CoA dehydrogenase gene mutation (c.319C>T) presents with clinical heterogeneity and is candidate founder mutation in individuals of Ashkenazi Jewish origin." in: Molecular genetics and metabolism, Vol. 93, Issue 2, pp. 179-89, 2008 (PubMed).

Catalog No. ABIN406378
$289.00
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