Interleukin 9 (IL9) (Middle Region) antibody

Details for Product No. ABIN406389
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Antigen
Synonyms IL9, IL-9, Il-9, P40, HP40
Epitope
Middle Region
(9), (3), (2), (1), (1), (1)
Reactivity
Human
(69), (26), (14), (1)
Host
Rabbit
(84), (6), (3), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(13), (5), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1)
Application
Western Blotting (WB)
(69), (44), (20), (11), (10), (9), (8), (6), (4), (4), (2), (2), (2), (1), (1)
Pubmed 1 reference available
Quantity 50 μg
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Catalog No. ABIN406389
289.00 $
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Immunogen Synthetic peptide directed towards the middle region of human IL9
Sequence SQMTNTTMQT RYPLIFSRVK KSVEVLKNNK CPYFSCEQPC NQTTAGNALT
Predicted Reactivity Human : 100 %
Characteristics This is a rabbit polyclonal antibody against IL9. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name IL9
Background IL9 is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding IL9 has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that IL9 is a determining factor in the pathogenesis of bronchial hyperresponsiveness. The protein encoded by this gene is a cytokine that acts as a regulator of a variety of hematopoietic cells. This cytokine stimulates cell proliferation and prevents apoptosis. It functions through the interleukin 9 receptor (IL9R), which activates different signal transducer and activator (STAT) proteins and thus connects this cytokine to various biological processes. The gene encoding this cytokine has been identified as a candidate gene for asthma. Genetic studies on a mouse model of asthma demonstrated that this cytokine is a determining factor in the pathogenesis of bronchial hyperresponsiveness.
Molecular Weight 14 kDa
Gene ID 3578
NCBI Accession NP_000581, NM_000590
UniProt P15248
Research Area Cancer, Cytokines, Innate Immunity
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 144 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
anti-Interleukin 9 (IL9) (Middle Region) antibody WB Suggested Anti-IL9 Antibody Titration: 0.2-1 ug/ml
Positive Control: Human Liver
Background publications Wu, Huang, Kato-Maeda et al.: "IL-9 is associated with an impaired Th1 immune response in patients with tuberculosis." in: Clinical immunology (Orlando, Fla.), Vol. 126, Issue 2, pp. 202-10, 2008 (PubMed).

Validation Images
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