HOXB3 antibody (N-Term)

Catalog No. ABIN406649

Product Details anti-HOXB3 Antibody

Target: HOXB3 (Homeobox B3 (HOXB3))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Rabbit, Horse, Dog, Pig, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HOXB3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: SCMRPGLAPE PLSAPPGSPP PSAAPTSATS NSSNGGGPSK SGPPKCGPGT

Predicted Reactivity: Cow: 100%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 93%, Rat: 93%

Characteristics: This is a rabbit polyclonal antibody against HOXB3. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human HOXB3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 431 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for HOXB3

Target: HOXB3 (Homeobox B3 (HOXB3))

Alternative Name: HOXB3 (HOXB3 Products)

Synonyms: Hox 2.7 antibody, hox2.7 antibody, hox2.7-A antibody, hoxb-3 antibody, hox2 antibody, hox2g antibody, hox-2.7 antibody, Z-92 antibody, hoxb3 antibody, id:ibd3053 antibody, wu:fc33f11 antibody, zgc:111819 antibody, Hox-2.7 antibody, HOX2 antibody, HOX2G antibody, 2.7 antibody, CHOX antibody, HOXB-3 antibody, hoxb3a antibody, homeobox B3 S homeolog antibody, homeobox B3 antibody, homeobox B3a antibody, homeo box B3 antibody, homeobox protein Hox-B3a-like antibody, hoxb3.S antibody, HOXB3 antibody, hoxb3 antibody, hoxb3a antibody, Hoxb3 antibody, LOC101061939 antibody

Background: HOXB3 belongs to ANTP homeobox family. It is a nuclear protein with a homeobox DNA-binding domain. HOXB3 gene is included in a cluster of homeobox B genes located on chromosome 17. The protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML).This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: HOX2, HOX2G, Hox-2.7
Protein Interaction Partner: CREBBP, EP300, HMGB1,
Protein Size: 431

Molecular Weight: 44 kDa

Gene ID: 3213

NCBI Accession: NM_002146, NP_002137

UniProt: P14651