Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN406665

Homeobox A11 (HOXA11) (Middle Region) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms Hoxa10, RGD1564605, RGD1566402, HOX1, HOX1I, Hox-1.9, Hoxa-11, GHOX1I, Xhoxa11, HOXA11
Epitope
»Alternatives Middle Region
Reactivity
»Alternatives Rabbit, Rat (Rattus), Mouse (Murine), Cow (Bovine), Dog (Canine), Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB)
Pubmed 1 reference available
Catalog no. ABIN406665
Quantity 50 µg
Price
289.00 $   Plus shipping costs $45.00
Shipping to
Availability Will be delivered in 2 to 3 Business Days
Immunogen The immunogen for anti-HOXA11 antibody: synthetic peptide directed towards the middle region of human HOXA11
Sequence FETAYGTPENLASSDYPGDKSAEKGPPAATATSAAAAAAA TGAPATSSSD
Predicted Reactivity Bovine : 100%, Human : 100%, Rabbit : 100%, Dog : 92%, Pig : 85%
Characteristics This is a rabbit polyclonal antibody against HOXA11. It was validated on Western Blot using a cell lysate as a positive control. We strive to provide antibodies covering each member of a whole protein family of your interest.
Purification Affinity Purified
Alternative Name HOXA11
Background In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. HOXA11 gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is involved in the regulation of uterine development and is required for female fertility. Mutations in this gene can cause radio-ulnar synostosis with amegakaryocytic thrombocytopenia.
Molecular Weight 34kDa
Gene ID 3207
NCBI Accession NP_005514, NM_005523
UniProt P31270
Research Area Chromatin and Nuclear Signaling, Transcription Factors
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water
Concentration 1mg/mL
Buffer Final anti-HOXA11 antibody concentration is 1 mg/mL in PBS buffer.
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Background publications Connell, Guess, Chen et al.: "HOXA11 is critical for development and maintenance of uterosacral ligaments and deficient in pelvic prolapse." in: The Journal of clinical investigation, Vol. 118, Issue 3, pp. 1050-5, 2008 (PubMed).

Alternatives for antigen "Homeobox A11 (HOXA11)", type "Antibodies"
Hosts (25), (13)
Reactivities (36), (19), (13), (13), (12), (1), (1)
Applications (26), (13), (10), (7), (4), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (2), (2), (2), (1), (1), (1), (1)
Beacon