anti-ARPC2 antibody (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa) (N-Term)

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Antigen
Synonyms arc34, p34-arc, pnas-139, pro2446, Arpc2, Arc-p34, 2210023N03Rik, 34kDa, p34-Arc, fk84a07, wu:fa22f07, wu:fk84a07, zgc:77769, ARC34, PNAS-139
Alternatives
Epitope
N-Term
(34), (16), (13), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Human, Mouse (Murine), Pig (Porcine), Rat (Rattus), Xenopus laevis
(90), (31), (30), (6), (5), (1), (1), (1), (1)
Host
Rabbit
(64), (22), (6)
Clonality
Polyclonal
Conjugate
This ARPC2 antibody is un-conjugated
(7), (7), (7), (3), (3), (3), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(78), (53), (32), (16), (11), (11), (5), (3), (3), (1), (1), (1), (1), (1)
Pubmed 2 references available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the N terminal of human ARPC2
Sequence MVLNVYCCFF QISDIQTMKI NQTILKEFIL VGFSVYPHVQ TFLFVVFFCL
Predicted Reactivity African clawed frog : 100 %, Bovine : 100 %, Human : 100 %, Mouse : 100 %, Pig : 100 %, Rat : 100 %, Chicken : 90 %, Horse : 80 %
Characteristics This is a rabbit polyclonal antibody against ARPC2. It was validated on Western Blot using a cell lysate as a positive control.
Purification Affinity Purified
Alternative Name ARPC2 (ARPC2 Antibody Abstract)
Background ARPC2 is one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of ARPC2, the p34 subunit, has yet to be determined. This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p34 subunit, has yet to be determined. Two alternatively spliced variants have been characterized to date. Additional alternatively spliced variants have been described but their full length nature has not been determined.
Molecular Weight 33 kDa
Gene ID 10109
NCBI Accession NP_005722, NM_005731
UniProt O15144
Research Area Signaling, Cytoskeleton, Microfilaments
Pathways RTK Signaling
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 300 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-ARPC2 antibody (Actin Related Protein 2/3 Complex, Subunit 2, 34kDa) (N-Term) (ABIN406714) WB Suggested Anti-ARPC2 Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Product cited in: Al Ghouleh, Rodríguez, Pagano et al.: "Proteomic analysis identifies an NADPH oxidase 1 (Nox1)-mediated role for actin-related protein 2/3 complex subunit 2 (ARPC2) in promoting smooth muscle cell migration." in: International journal of molecular sciences, Vol. 14, Issue 10, pp. 20220-35, 2013 (PubMed).

Background publications Cai, Marshall, Uetrecht et al.: "Coronin 1B coordinates Arp2/3 complex and cofilin activities at the leading edge." in: Cell, Vol. 128, Issue 5, pp. 915-29, 2007 (PubMed).

Catalog No. ABIN406714
$289.00
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