anti-CDK7 antibody (Cyclin-Dependent Kinase 7) (C-Term)

Details for Product anti-CDK7 Antibody No. ABIN406738, Supplier: Login to see New
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Antigen
Synonyms
CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk7, p40[MO15], MO15, cak1, stk1, cdkn7, p39mo15, p40MO15, CAK1, CDKN7, HCAK, STK1, p39MO15, AI323415, AI ... show more
CD 7, CDK7, CG3319, DmCDK7, DmCdk7, DmMO15, DmMo15, Dmcdk7, Dmel\\CG3319, Mo15, cdk-7, cdk7, dCdk7, p40[MO15], MO15, cak1, stk1, cdkn7, p39mo15, p40MO15, CAK1, CDKN7, HCAK, STK1, p39MO15, AI323415, AI528512, C230069N13, Cdkn7, Crk4, zgc:85821, C-MOS show less
Alternatives
Epitope
C-Term
(38), (35), (17), (16), (7), (6), (5), (5), (5), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Cow (Bovine), Dog (Canine), Human, Mouse (Murine), Pig (Porcine)
(196), (47), (18), (4), (4), (4), (3), (2), (1)
Host
Rabbit
(149), (59), (1)
Clonality
Polyclonal
Conjugate
This CDK7 antibody is un-conjugated
(8), (8), (6), (6), (6), (6), (2), (1), (1)
Application
Immunohistochemistry (IHC), Western Blotting (WB)
(175), (96), (79), (40), (25), (21), (20), (18), (18), (11), (9), (6), (3), (2), (1), (1), (1)
Pubmed 1 reference available
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Quantity 50 μg
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Immunogen Synthetic peptide directed towards the C terminal of human CDK7
Sequence NRPGPTPGCQ LPRPNCPVET LKEQSNPALA IKRKRTEALE QGGLPKKLIF
Predicted Reactivity Bovine : 100 %, Horse : 100 %, Human : 100 %, Pig : 100 %, Dog : 90 %, Guinea pig : 90 %, Mouse : 80 %, Rat : 80 %
Characteristics This is a rabbit polyclonal antibody against CDK7. It was validated on Western Blot.
Purification Affinity Purified
Alternative Name CDK7 (CDK7 Antibody Abstract)
Background Cdk7 is the catalytic subunit of the CDK-activating kinase (CAK) complex, a serine-threonine kinase. CAK activates the cyclin-associated kinases CDC2/CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcripti
Molecular Weight 39 kDa
Gene ID 1022
NCBI Accession NP_001790, NM_001799
UniProt P50613
Research Area Cell Cycle
Pathways Cell Division Cycle, DNA Damage Repair
Application Notes Optimal working dilutions should be determined experimentally by the investigator.
Comment

Antigen size: 346 AA

Restrictions For Research Use only
Format Lyophilized
Reconstitution Add 50 µL of distilled water.
Concentration 1 mg/mL
Buffer PBS buffer with 2 % sucrose
Handling Advice Avoid repeated freeze-thaw cycles.
Storage -20 °C
Storage Comment For longer periods of storage, store at -20 °C
Supplier Images
Western Blotting (WB) image for anti-CDK7 antibody (Cyclin-Dependent Kinase 7) (C-Term) (ABIN406738) anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody
Immunohistochemistry (IHC) image for anti-CDK7 antibody (Cyclin-Dependent Kinase 7) (C-Term) (ABIN406738) anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-CDK7 antibody (Cyclin-Dependent Kinase 7) (C-Term) (ABIN406738) anti-Cyclin-Dependent Kinase 7 (CDK7) (C-Term) antibody (Image 3)
Background publications Tassan, Schultz, Bartek et al.: "Cell cycle analysis of the activity, subcellular localization, and subunit composition of human CAK (CDK-activating kinase)." in: The Journal of cell biology, Vol. 127, Issue 2, pp. 467-78, 1994 (PubMed).

Catalog No. ABIN406738
$289.00
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