BMI-1 antibody
| Antigen |
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| Clonality |
Polyclonal |
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Host
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Reactivity
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Human, Mouse (Murine), Rat (Rattus), Cow (Bovine), Dog (Canine), Cat (Feline)
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Application
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| Catalog no. |
ABIN411436 |
| Quantity |
100 µg (0.5 mg/ml) |
| Price |
225.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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100 ug affinity purified rabbit anti-BMI-1 polyclonal antibody. Reacts with human/mouse/rat/bovine/dog/cat. Detects 34 kDa PMI-1 in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3930BP-50) is available separately.
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Gene ID
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307151
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Immunogen
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Synthetic peptide surrounding amino acid 312 of rat BMI-1
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Polycomb group (PcG) genes encode chromatin proteins that are involved in the maintenance of cellular memory through epigenetic chromatin modifications. Bmi-1 has been identified among the PcG genes as a potent oncogene that plays an important role in the regulation of cell proliferation by suppressing the p16-dependant pathway. Bmi-1 may be use as a therapeutic target for studying stem cell proliferation and renewal.
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Application Notes
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Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~34 kDa of Bmi-1 in Jurkat cell lysate and rat kidney tissue lysate. Reactivity to other species has not been tested.
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Concentration
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0.5 mg/ml
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Purification
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Affinity Purified Antibody
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Buffer
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100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
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Storage
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Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
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Restrictions
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For Research Use only
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Alternatives for antigen "BMI-1", type "Antibodies"
Alternatives 
