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BRK antibody
| Antigen | BRK |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human, Mouse (Murine), Rat (Rattus) |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN411443 |
| Quantity | 100 µg (0.5 mg/ml) |
| Price | 225.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | 100 ug affinity purified rabbit anti-Brk polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Blocking peptide (Cat.# 3847BP-50) is also available. |
| Gene ID | 5753 |
| Immunogen | Synthetic peptide corresponding to residues surrounding amino acids 508 of human Brk |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Breast tumor kinase, Brk (also known as PTK6), is a member of intracellular tyrosine kinase family that is thought to be related to Src family of tumor related kinases. Brk is expressed in breast carcinomas but not in normal breast tissue. The presence of Brk in the nucleus appears to be linked to suppression of tumor progression and has been shown to undergo autophosphorylation. |
Application Details
| Application Notes | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~57 kDa Brk of human, mouse, and rat origins. Reactivity to other species has not been tested. |
| Concentration | 0.5 mg/ml |
| Purification | Affinity Purified Antibody |
| Buffer | 100 µg (0.5 mg/ml) affinity purified rabbit anti-Brk polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Storage | Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use. |
| Research Area | Cancer, Tyrosine Kinases |
| Restrictions | For Research Use only |
