Add to Basket
Order hotline:
+1 404 474 4654
+1 888 205 9894 (TF)

CAMP Responsive Element Binding Protein 1 (CREB1) antibody

Antigen

CAMP Responsive Element Binding Protein 1 (CREB1)
Synonyms CREB, MGC9284, Creb, Creb-1, AV083133, 2310001E10Rik, 3526402H21Rik, JAL, hJAL, ATCE1, CREB3, CREB4, AIBZIP, CREB1, creb1, MGC52669, creb, MGC69285, MGC55598, zgc:55598, Creb1, DKFZp468J2311
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human, Mouse (Murine), Rat (Rattus)
Application
Alternatives Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)
Catalog no. ABIN411455
Quantity 100 µg  (0.5 mg/ml)
Price 225.00 $   Plus shipping costs $35.00
Shipping to
Availability Ships within 7 to 10 Business Days

Additional Information
Application Details Alternatives Secondary Antibodies back to top

Characteristics 100 ug Rabbit Polyclonal Antibody. Reacts with human/mouse/rat. Detect 43 kDa CREB and also 28-36 kDa CREB isoforms in Western blot analysis. Blocking peptide (Cat.# 3360RBP-50) is available separately.
Alternative name CREB
Gene ID 81646
Immunogen Synthetic peptide surrounding amino acid 109 of rat CREB
Isotype IgG  (Matching secondary antibodies)
Description Transcription factor CREB binds the cAMP response element (CRE) and activates transcription in response to a variety of extracellular signals including neurotransmitters, hormones, membrane depolarization, and growth or neurotrophic factors. Protein kinase A and the calmodulin-dependent protein kinase CaMKII stimulate CREB phosphorylation at Ser133, a key regulatory site controlling transcriptional activity. Phosphorylation at Ser133 is also mediated by p44/42 MAP kinase, p90RSK, p38 MAP kinase and MSK1. CREB appears to play an important role in learning and memory in both flies and mice.
Specificity The antibody recognizes 43 kDa CREB from samples of human, mouse and rat origins.

Application Details
Alternatives Secondary Antibodies back to top

Application Notes Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 43 kDa CREB from samples of human, mouse and rat origins.
Concentration 0.5 mg/ml
Purification Affinity Purified Antibody
Buffer 100 µg (0.5 mg/ml) purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
Storage Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
Restrictions For Research Use only

Alternatives
Application Details Secondary Antibodies back to top

Alternatives for antigen "CAMP Responsive Element Binding Protein 1 (CREB1)", type "Antibodies"
Hosts Rabbit (127), Mouse (25)
Reactivities Human (144), Rat (Rattus) (109), Mouse (Murine) (108), Cow (Bovine) (37), Sheep (Ovine) (34), Dog (Canine) (33), Pig (Porcine) (33), Chicken (32), Monkey (2), Xenopus laevis (2), Rabbit (1), Zebrafish (Danio rerio) (1)
Applications Western Blotting (WB) (93), Immunohistochemistry (IHC) (50), Immunofluorescence (IF) (47), Flow Cytometry (FACS) (37), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (36), Enzyme Immunoassay (EIA) (20), ELISA (19), Immunoprecipitation (IP) (13), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (4), Immunohistochemistry (Frozen Sections) (IHC (fro)) (3), Dot Blot (Dot) (2), ELISA (Detection) (2), Immunoelectron Microscopy (IEM) (2), Electrophoretic Mobility-Shift Assay (EMSA) (1)
Conjugates Biotin (3), Alexa Flour 488 (2), Alexa Fluor 350 (2), Alexa Fluor 488 (2), Alexa Fluor 555 (2), Alexa Fluor 647 (2), Cy3 (2), Cy5 (2), Cy5.5 (2), Cy7 (2), FITC (2), Gold (2), HRP (2), PE (2), PE,Cy3 (2), PE,Cy5 (2), PE,Cy5.5 (2), PE,Cy7 (2), RBITC (2)
Epitopes pSer133 (26), pSer129 (9), pS133 (4), pSer142 (4), N-Term (1), p43 (1), pSer121 (1)