Diacylglycerol O-Acyltransferase 1 (DGAT1) antibody

Antigen: Diacylglycerol O-Acyltransferase 1 (DGAT1)

Synonyms: DGAT, ARGP1, Dgat, C75990, D15Ertd23e, MGC139064, dgat1, zgc:77691, wu:fd36g11, DGAT1, ABX45, AS11, ATDGAT, DIACYLGLYCEROL ACYLTRANSFERASE, F27F23.24, RDS1, TAG1, TRIACYLGLYCEROL BIOSYNTHESIS DEFECT 1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411463

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-DGAT1 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Blocking peptide (Cat.# 3845BP-50) is also available.

Alternative name: DGAT1

Gene ID: 8694

Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 308 of mouse DGAT-1

Isotype: IgG  (Matching secondary antibodies)

Description: Diacylglycerol acyltransferase is also known as DGAT1 is a microsomal enzyme. It is involved in the synthesis of fatty acids into triglycerides. DGAT utilizes diacylglycerol (DAG) and fatty acyl CoA as substrates to synthesize triacylglycerol. DGAT plays an important role in the metabolism of cellular diacylglycerol and is essential in the physiologic processes of higher eukaryotes that includes triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60 kDa DGAT-1 of human, mouse, and rat origins. Reactivity to other species has not been tested.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-DGAT-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Cancer, Fatty Acids, Metabolism

Restrictions: For Research Use only