Dentin Matrix Acidic phosphoprotein 1 (DMP1) antibody

Antigen: Dentin Matrix Acidic phosphoprotein 1 (DMP1)

Synonyms: ARHP, ARHR, DMP-1, PP, Dmp, AV020965, MGC130441, DENTMAT, DMP1

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411468

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-DMP1 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Blocking peptide (Cat.# 3844BP-50) is also available.

Alternative name: DMP1

Gene ID: 25312

Immunogen: Synthetic peptide corresponding to residues surrounding amino acids 21 of rat DMP-1

Isotype: IgG  (Matching secondary antibodies)

Description: DMP-1 (Dentin matrix protein1) is a member of the integrin ligand N-linked glycoprotein family.It is mostly found in bone, tooth and hypertrophic cartilage. DMP-1 plays an important role in dentin and bone mineralization. DMP-1 has multiple serine, glutamic acid and aspartic acid residues, a GAG attachement site and RGD motif. DMP-1 is proteolytically proceesed into mulitple fragemtns in the extracellular matrix (ECM) of bone and dentin.

Specificity: The antibody recognizes ~60-130 kDa DMP- 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~60-130 kDa DMP- 1 of human, mouse, and rat origins. Reactivity to other species has not been tested.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-DMP-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Organogenesis, Extracellular Matrix

Restrictions: For Research Use only

Publications

Publications: Lin, Xu, Liu et al.: "KLF4 Promotes the Odontoblastic Differentiation of Human Dental Pulp Cells." in: Journal of endodontics, Vol. 37, Issue 7, pp. 948-54, 2011 (PubMed).