Dystrophin (DMD) antibody

Antigen: Dystrophin (DMD)

Synonyms: DMD, MGC155049, Dmd, MGC83347, DKFZp459C1629, dmd, MGC79631, DKFZp468A1620, Dp71, cb664, zfDYS, im:6911785, zgc:110165, BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, mdx, pke, Dp427, DXSmh7, DXSmh9, RATDMD, DNADMD1, CG17750, CG31175, CG7240, CG7243, CG7344, DLP, DLP1, DLP186, DLP2, DLP3, DmDLP, DmDYS, Dp205, GI3046716, dmDp186, DmelCG34157, CG34157

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411476

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-Dystrophin polyclonal antibody. Reacts with human/mouse/rat. Detects 60 kDa Dystrophin in Western blot analysis. Other applicatiosn have not been determined. Blocking peptide (Cat.# 3586RBP-50) is available separately.

Alternative name: Dystrophin

Gene ID: 1756

Immunogen: Synthetic peptide surrounding amino acid 3656 of human Dystrophin

Isotype: IgG  (Matching secondary antibodies)

Description: Dystrophin is one of the actin-binding proteins that are involved in anchoring the cytoskeleton to the plasma membrane. Dystrophin expression is found in muscle brain tissues, where it is located to the inner surface of the plasma membrane. It is suggested that alternative splicing of the caboxy terminus allows dystrophin to interact with a variety of proteins. Loss of dystrophin-associated proteins in Duchenne afflicted muscle is due to the absence of dystrophin rather than to muscle degradation and lack of dystrophin results in the loss of linkage between the cytoskeleton and extracellular matrix.

Specificity: The antibody detects ~60 and 130 kDa of Dystrophin in samples from human, mouse and rat origins. Reactivity to other species has not been determined.

Synonyms: DMD, MGC155049, Dmd, MGC83347, DKFZp459C1629, dmd, MGC79631, DKFZp468A1620, Dp71, cb664, zfDYS, im:6911785, zgc:110165, BMD, CMD3B, DXS142, DXS164, DXS206, DXS230, DXS239, DXS268, DXS269, DXS270, DXS272, mdx, pke, Dp427, DXSmh7, DXSmh9, RATDMD, DNADMD1, CG17750, CG31175, CG7240, CG7243, CG7344, DLP, DLP1, DLP186, DLP2, DLP3, DmDLP, DmDYS, Dp205, GI3046716, dmDp186, DmelCG34157, CG34157

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects ~60 and 130 kDa of Dystrophin in samples from human, mouse and rat origins. Reactivity to other species has not been determined.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-Dystrophin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol and 0.01% Thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Restrictions: For Research Use only