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ECM antibody

Antigen

ECM

Clonality Polyclonal
Host

Rabbit

Reactivity

Human, Mouse (Murine), Rat (Rattus)

Application
Western Blotting (WB)
Catalog no. ABIN411477
Quantity 100 µg  (0.5 mg/ml)
Price 225.00 $   Plus shipping costs $35.00
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Additional Information

Characteristics 100 ug affinity purified rabbit anti-ECM polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blotting. Other applications have not been determined. Blocking peptide (Cat.# 3843BP-50) is available separately.
Gene ID 13601
Immunogen Synthetic peptide corresponding to residues surrounding amino acids 546 of mouse ECM-1
Isotype IgG  (Matching secondary antibodies)
Description Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the main components of membrane phospholipid, triglycerides and cholesterol esters. SCD plays an important role in cellular cholesterol homeostasis and also in the secretion processes of triacylglycerol and phospholipid. Inhibition of SCD could be a useful treatment for metabollic disorders such as obesity and hepatic steatosis.

Application Details

Application Notes Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~61 kDa ECM-1 of human, mouse, and rat origins. Reactivity to other species has not been tested.
Concentration 0.5 mg/ml
Purification Affinity Purified Antibody
Buffer 100 µg (0.5 mg/ml) affinity purified rabbit anti-ECM-1 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Storage Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
Restrictions For Research Use only