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Granzyme B P antibody
| Antigen | Granzyme B P |
| Clonality | Polyclonal |
| Host |
Rabbit |
| Reactivity |
Human, Mouse (Murine), Rat (Rattus) |
| Application |
Western Blotting (WB)
|
| Catalog no. | ABIN411497 |
| Quantity | 100 µg (0.5 mg/ml) |
| Price | 225.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | 100 ug affinity purified rabbit anti-Granzyme B polyclonal antibody. Reacts with human/mouse/rat. Detects 27 kDa Granzyme B in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3073RBP-50) is available separately. |
| Gene ID | 3002 |
| Immunogen | Synthetic peptide corresponding to residues surrounding amino acid 221 of human Granzyme B |
| Isotype | IgG (Matching secondary antibodies) |
| Description | Granzyme B is a 27 kDa serine protease stored in granules of activated cytotoxic T cells and NK cells. Upon target cell contact, granzyme B is directionally exocytosed and assisted by perforin, enters the target cell. With its unique substrate specificity (granzyme B cleaves after Asp), granzyme B processes and activates various pro-caspases thereby inducing apoptosis in the target cell. |
Application Details
| Application Notes | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. |
| Concentration | 0.5 mg/ml |
| Purification | Affinity Purified Antibody |
| Buffer | 100 µg (0.5 mg/ml) affinity purified polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal. |
| Storage | Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use. |
| Restrictions | For Research Use only |
