Hepatocyte Nuclear Factor 4 alpha (HNF4A) antibody

Antigen: Hepatocyte Nuclear Factor 4 alpha (HNF4A)

Synonyms: TCF, HNF4, MODY, MODY1, NR2A1, TCF14, HNF4a7, HNF4a8, HNF4a9, NR2A21, FLJ39654, HNF4alpha, HNF4A

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human

Application: ELISA, Western Blotting (WB)

Catalog no.: ABIN411506

Additional Information

Characteristics: 100 µg (0.25 mg/ml) affinity purified antibody. Reacts with human. Tested in ELISA and Western Blot.

Alternative name: HNF4A

Gene ID: 3172

Immunogen: Synthetic peptide selected from the center region of human HNF4A

Isotype: IgG  (Matching secondary antibodies)

Description: HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in the HNF4A gene have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

Specificity: The antibody detects a ~ 53 kDa band, corresponding to the expected molecular mass of HNF4 on immunoblots.

Application Details

Application Notes: The antibody can be used for ELISA (0.25 µg/ml) and Western blotting (2.5 – 5.0 µg/ml).

Concentration: 0.25 mg/ml

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation

Buffer: 100 µg (0.25 mg/ml) purified rabbit Ig polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Restrictions: For Research Use only