HtrA Serine Peptidase 2 (HTRA2) antibody

Antigen: HtrA Serine Peptidase 2 (HTRA2)

Synonyms: OMI, PARK13, PRSS25, Omi, mnd2, Prss25, AI481710, HTRA2

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411508

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-HtrA2/Omi polyclonal antibody. Reacts with human/mouse/rat. Tested in Western blot analysis. Other applicationa have not been determined. Jurkat cell lysates (Cat.# 2401-100), 3T3 cell lysate and rat kidney tissue lysate can be used as positive controls.

Alternative name: HtrA2/Omi

Gene ID: 27429

Immunogen: Synthetic peptide surrounding amino acid 421 of human HtrA2/Omi

Isotype: IgG  (Matching secondary antibodies)

Description: Human HtrA2 (also designated Omi) is a novel member of the HtrA serine protease family and is highly homologous to HtrA (also known as L56 and HtrA1). HtrA2 is ubiquitously expressed nuclear protease that is capable of autoproteolysis. The HtrA2 protein exists as two polypeptides of 38 and 40 kDa and as an alternatively spliced form called D-Omi, which is predominately expressed in the kidney, colon and thyroid. Like HtrA, HtrA2 is involved in the degradation aberrantly folded proteins during conditions of cellular stress, suggesting that it may possess a chaperone-like role under normal conditions.

Application Details

Application Notes: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Restrictions: For Research Use only