Mitofusin 2 (MFN2) antibody

Antigen: Mitofusin 2 (MFN2)

Synonyms: HSG, MARF, CMT2A, CPRP1, CMT2A2, KIAA0214, Fzo, D630023P19Rik, MGC81251, MFN2, hsg, marf, cmt2a, cprp1, cmt2a2, DKFZp459G151

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411536

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-Mitofusin 2 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western Blot. Other applications have not been determined.

Alternative name: Mitofusin 2

Gene ID: 9927

Immunogen: Synthetic peptide corresponding to residues surrounding amino acid 719 of human Mitofusin 2

Isotype: IgG  (Matching secondary antibodies)

Description: Mitofusin 2 (Mfn 2) is mostly expressed in the heart and muscle tissues. It is a transmembrane protein that mediates mitochondria fusion and plays a central role in the maintenance of mitochondrial morphology. A GTPase domain is required for the function of Mitofusin proteins. Mutations in Mfn2 can lead to Charcot-Marie-Tooth disease, a common inherited disorder of the peripheral nervous system. Mfn2 may also be associated with obesity and/or apoptosis.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes 68 kDa and 86 kDa bands from samples of human, mouse, rat origins. Reactivity to other species has not been tested.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Neurology, Metabolism, Apoptosis/Necrosis, Organelles

Restrictions: For Research Use only