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Antibodies
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anti-Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) antibody
Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11) antibody
| Antigen |
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| Synonyms |
ST3, SL-3, STMY3 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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Western Blotting (WB) (27), Immunofluorescence (IF) (21), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunoprecipitation (IP) (11), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (IHC) (4), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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| Catalog no. |
ABIN411537 |
| Quantity |
100 µg (0.5 mg/ml) |
| Price |
225.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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100 ug affinity purified rabbit anti-MMP-11 polyclonal antibody. Reacts with human/mouse/rat. Detects the latent form (~68 kDa) and the activated forms (~55 kDa and ~40 kDa) of MMP-11 in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3531RBP-50) is available separately.
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Alternative name
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MMP-11
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Gene ID
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17385
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Immunogen
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Synthetic peptide surrounding amino acid 464 of mouse MMP-11
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Isotype
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IgG (Matching secondary antibodies)
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Description
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The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies.
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Specificity
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The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
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Application Notes
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Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Blocking peptide (3531RBP-50) is available separately. The antibody recognizes the latent form (~68 kDa) and the active forms (~55 kDa and ~40 kDa) of MMP-11 from human, mouse, and rat origins.
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Concentration
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0.5 mg/ml
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Purification
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Affinity Purified Antibody
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Buffer
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100 µg (0.5 mg/ml) immunoaffinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.
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Storage
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Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
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Restrictions
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For Research Use only
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Alternatives for antigen "Matrix Metallopeptidase 11 (Stromelysin 3) (MMP11)", type "Antibodies"
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Hosts
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Rabbit (34), Mouse (13)
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Reactivities
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Human (45), Rat (Rattus) (27), Mouse (Murine) (26), Cow (Bovine) (17), Dog (Canine) (17), Pig (Porcine) (16), Chicken (1), Horse (Equine) (1)
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Applications
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Western Blotting (WB) (27), Immunofluorescence (IF) (21), Flow Cytometry (FACS) (18), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunoprecipitation (IP) (11), Enzyme Immunoassay (EIA) (4), Immunohistochemistry (IHC) (4), ELISA (3), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (2), Immunocytochemistry (ICC) (1), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
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Conjugates
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Biotin (4), Alexa Flour 488 (1), Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1), RBITC (1)
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Epitopes
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C-Term (3)
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Alternatives 
