Notch 1 (NOTCH1) antibody
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| Synonyms |
hN1, TAN1, Mis6, Tan1, lin-12, 9930111A19Rik, NOTCH, NOTCH1, notch1, hn1, tan1, notch, xotch, xnotch, notch-1, xnotch1 |
| Clonality |
Polyclonal |
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Host
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Reactivity
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Application
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| Catalog no. |
ABIN411548 |
| Quantity |
100 µg (0.5 mg/ml) |
| Price |
225.00 $ Plus shipping costs $35.00
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| Shipping to |
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| Availability |
Ships within 7 to 10 Business Days |
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Characteristics
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100 ug affinity purified rabbit anti-Notch 1 polyclonal antibody. Reacts with human/mouse/rat. Tested in Western Blot. Other applications have not been determined.
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Alternative name
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Notch 1
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Gene ID
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18128
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Immunogen
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Synthetic peptide corresponding to residues surrounding amino acid 1760 of mouse Notch1
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Isotype
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IgG (Matching secondary antibodies)
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Description
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Notch proteins are transmembrane receptor that regluate cell fate decisions. Four Notch homologs have been identified in mammals namely Notch 1, Notch 2, Notch 3 and Notch 4. The membrane ligand for Notch includes Jagged 1, Jagged 2 and Delta. Notch 1 is a 270 kDa transmembrane receptor that can be activated by Delta (Dl) ligand. Activation of Notch 1 will result in the proteolytic cleavage of Notch 1 into a 120 kDa length protein.
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Specificity
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The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
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Application Notes
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Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes a 120 kDa band from samples of human and mouse origins. Reactivity to other species has not been tested.
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Concentration
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0.5 mg/ml
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Purification
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Affinity Purified Antibody
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Buffer
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100 µg (0.5mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA and 0.01% thimerosal.
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Storage
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Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.
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Restrictions
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For Research Use only
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Alternatives for antigen "Notch 1 (NOTCH1)", type "Antibodies"
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Hosts
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Mouse (34), Rabbit (24), Hamster (2), Goat (1)
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Reactivities
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Human (40), Mouse (Murine) (31), Rat (Rattus) (10)
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Applications
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Western Blotting (WB) (32), Flow Cytometry (FACS) (28), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (16), Immunohistochemistry (Frozen Sections) (IHC (fro)) (9), ELISA (8), Enzyme Immunoassay (EIA) (6), Immunohistochemistry (IHC) (6), Immunoprecipitation (IP) (3), Immunofluorescence (IF) (2), Immunocytochemistry (ICC) (1)
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Conjugates
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PE (4), Biotin (2), RPE (1)
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Epitopes
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C-Term (5), Cleaved N-Term (1), Cleaved-Val1754 (1), Intra (1), N-Term (1), internal (1)
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Alternatives 
