P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) antibody

Antigen: P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7)

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus), Dog (Canine)

Application: Western Blotting (WB)

Catalog no.: ABIN411550

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-PAK5/PAK7 polyclonal antibody. Reacts with human/mouse/rat/dog. Detects 80 kDa PAK5/PAK7 in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3928BP-50) is available separately.

Alternative name: PAK5/PAK7

Gene ID: 57144

Immunogen: Synthetic peptide surrounding amino acid 90 of human PAK5/PAK7

Isotype: IgG  (Matching secondary antibodies)

Description: The PAK (p21-activated kinase) family of serine/threonine kinases plays an important role in multiple cellular processes, including cytoskeletal reorganization, MAPK signaling, apoptotic signaling, etc. PAK 5 is known for promoting neurite outgrowth and thus predominantly expressed in the brain. PAK 5 contains CDC42/Rac1and has shown to bind CDC42 in the presence of GTP. PAK 5 also plays an important role in inhibiting apoptotic cascade through BAD phosphorylation.

Application Details

Application Notes: Western blot analysis (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~80 kDa of Pak5/PAK7 from samples of human, mouse, rat and dog origins. Reactivity to other species has not been determined.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-human PAK5/PAK7 polyclonal antibody in phosphate (PBS, pH 7.2) containing 30% glycerol, 0.5 % BSA and 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Restrictions: For Research Use only