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Phospho-IRS (Ser616) antibody
| Antigen | Phospho-IRS |
| Epitope |
Ser616 |
| Clonality | Monoclonal (HIR-B1) |
| Host |
Mouse |
| Reactivity |
Human |
| Application |
Indirect ELISA (iELISA), Western Blotting (WB)
|
| Catalog no. | ABIN411558 |
| Quantity | 100 µg (1.0 mg/ml) |
| Price | 265.00 $ Plus shipping costs $35.00 |
| Shipping to |
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| Availability | Ships within 7 to 10 Business Days |
Additional Information
| Characteristics | 100 µg (1.0 mg/ml) affinity purified antibody. Reacts with human. Tested in indirect ELISA and WB. |
| Alternative name | Phospho-IRS (Ser616) |
| Gene ID | 3667 |
| Immunogen | Synthetic peptide phosphorylated at Ser 616 site |
| Isotype | IgG1 (Matching secondary antibodies) |
| Clone | HIR-B1 |
| Description | Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups. |
Application Details
| Application Notes | The antibody can be used for indirect ELISA and WB. |
| Concentration | 1.0 mg/ml |
| Purification | Affinity Purified Antibody |
| Buffer | 100 µg (1.0 mg/ml) purified mouse monoclonal antibody supplied in PBS with 0.05% (W/V) sodium azide. |
| Storage | Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use. |
| Restrictions | For Research Use only |
