PTEN Induced Putative Kinase 1 (PINK1) antibody

Antigen: PTEN Induced Putative Kinase 1 (PINK1)

Synonyms: BRPK, PARK6, FLJ27236, BEST:GH23468, PINK1, dPINK1, DmelCG4523, CG4523, AU042772, AW557854, mFLJ00387, 1190006F07Rik, MGC189438, wu:fc39e12, zgc:101729

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus)

Application: Western Blotting (WB)

Catalog no.: ABIN411563

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-PINK1 polyclonal antibody. Reacts with human/mouse/rat. Detects 55 kDa and 66 kDa PINK1 from samples of human/mouse/rat origins. Tested in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3929BP-50) is available separately.

Alternative name: PINK1

Gene ID: 68943

Immunogen: Synthetic peptide surrounding amino acid 488 of mouse PINK1

Isotype: IgG  (Matching secondary antibodies)

Description: PINK1 (PTEN-induced putative kinase 1) is a serine/threonine protein kinase found in mitochondria. PINK1 protects cell from .stress-induced mitochondrial dysfunction. Mutation in this gene is associated with the early onset of Parkinson's disease.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes 55 kDa and 63 kDa isoforms of PINK1 in samples from human, nouse and rat origins. Reactivity to other species has not been tested.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Signaling, Metabolism

Restrictions: For Research Use only