SCD antibody

Antigen: SCD

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus), Pig (Porcine), Hamster

Application: Western Blotting (WB)

Catalog no.: ABIN411581

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-DCS polyclonal antibody. Reacts with human/mouse/rat/pig/hamster. Tested in Western blot. Other applications have not been determined. Blocking peptide (Cat.# 3875BP-50) is available separately.

Gene ID: 83792

Immunogen: Synthetic peptide surrounding amino acid 206 of rat SCD

Isotype: IgG  (Matching secondary antibodies)

Description: Stearoyl-CoA desaturase (SCD) is a regulatory enzyme involved in the synthesis of oleate and palmitoleate. Oleate and palmitoleate are the main components of membrane phospholipid, triglycerides and cholesterol esters. SCD plays an important role in cellular cholesterol homeostasis and also in the secretion processes of triacylglycerol and phospholipid. Inhibition of SCD could be a useful treatment for metabollic disorders such as obesity and hepatic steatosis.

Specificity: The antibody recognizes a ~37 kDa SCD. Rat kidney tissue lysate can be used as a positive control. Blocking peptide (Cat.# 3875BP-50) is available separately.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been determined. The antibody recognizes a ~37 kDa SCD. Rat kidney tissue lysate can be used as a positive control.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit anti-SCD polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Cancer, Fatty Acids, Metabolism

Restrictions: For Research Use only