Toll-Like Receptor 10 (TLR10) antibody

Antigen: Toll-Like Receptor 10 (TLR10)

Synonyms: CD290, MGC104967, MGC126398, MGC126399, TLR10, MGC140623

Clonality: Polyclonal

Host: Rabbit

Reactivity: Human, Mouse (Murine), Rat (Rattus), Cow (Bovine)

Application: Western Blotting (WB)

Catalog no.: ABIN411607

Additional Information

Characteristics: 100 ug affinity purified rabbit anti-TLR10 polyclonal antibody. Reacts with human/mouse/rat/bovine. Detects ~75 kDa TLR10 in Western blot analysis. Other applications have not been determined. Blocking peptide (Cat.# 3932BP-50) is available separately.

Alternative name: TLR10

Gene ID: 81793

Immunogen: Synthetic peptide surrounding amino acid 513 of human TLR10

Isotype: IgG  (Matching secondary antibodies)

Description: The Toll-like receptor (TLR) family of proteins are characterized by a highly conserved Toll homology (TH) domain, which is essential for Toll-induced signal transduction. TLRs require adapter molecule such as MyD88 and TIRAP to activate various kinases and transcription factors. TLR10 is homologous to TLRs 1 and 6 and is highly expressed in the lymphoid tissues.

Specificity: The antibody recognizes ~75 kDa and 94 kDa isoforms of TLR10 in Jurkat cell lysate. Reactivity to other species has not been tested.

Application Details

Application Notes: Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody recognizes ~75 kDa and 94 kDa isoforms of TLR10 in Jurkat cell lysate. Reactivity to other species has not been tested.

Concentration: 0.5 mg/ml

Purification: Affinity Purified Antibody

Buffer: 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal.

Storage: Store at -20°C. Shelf life: 12 months. The antibody solution should be gently mixed before use.

Research Area: Immunology, Innate Immunity

Restrictions: For Research Use only