BCL2 antibody (B-Cell CLL/lymphoma 2)

Details for Product anti-BCL2 Antibody No. ABIN4283360, Supplier: Log in to see
Antigen
  • Bcl-2
  • PPP1R50
  • bcl-2
  • AW986256
  • C430015F12Rik
  • D630044D05Rik
  • D830018M01Rik
  • BCL-2
  • Bcl2
  • B-cell CLL/lymphoma 2
  • B cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2
  • B-cell leukemia/lymphoma 2-like
  • B-cell CLL/lymphoma 2 protein
  • BCL2
  • Bcl2
  • LOC100224888
  • bcl2
  • LOC100359045
  • BCL-2
Alternatives
anti-Human BCL2 antibody for Flow Cytometry
Reactivity
Dog (Canine), Human, Mouse (Murine)
1060
257
213
54
27
22
18
18
5
4
4
3
2
2
2
2
Host
Rabbit
577
548
19
6
2
2
2
Clonality
Polyclonal
Conjugate
This BCL2 antibody is un-conjugated
50
50
45
38
25
24
22
16
15
14
14
14
14
14
14
14
13
13
13
7
7
7
6
6
6
6
6
6
6
2
2
1
1
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Western Blotting (WB)
838
397
388
342
336
326
234
195
171
81
40
15
14
13
12
11
9
4
3
2
1
1
1
1
1
1
1
Options
Supplier
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Supplier Product No.
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Immunogen A synthetic peptide corresponding to amino acids 41-54 (GAAPAPGIFSSQPG) of human Bcl-2 was used as immunogen, GenBank no. NP_000648.2. This sequence is 100% conserved in human Bcl-2 alpha (239 aa) and beta (205 aa) isoforms.
Specificity Bcl-2
Purification Unpurified
Alternative Name Bcl-2 (BCL2 Antibody Abstract)
Background Gene Symbol: BCL2
Gene ID 596
NCBI Accession NP_000648
Research Area Apoptosis/Necrosis, Cancer
Pathways MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Application Notes Western Blot 1:1000-1:2000, Immunohistochemistry, Immunoprecipitation 1:50-1:200, Immunohistochemistry-Paraffin 1:1000-1:5000
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer Whole antisera
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Western Blot: Bcl-2 Antibody [ABIN42833608] - Analysis of Bcl-2 in whole cell lysate ...
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Western Blot: Bcl-2 Antibody [ABIN42833608] - Analysis of Bcl-2 in 293T cell lysate (...
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Western Blot: Bcl-2 Antibody [ABIN42833608] - Analysis of Bcl-2 using this antibody a...
Western Blotting (WB) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Western Blot: Bcl-2 Antibody - WB analysis of whole cell lysate (WCL) of Jurkat cell...
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Immunohistochemistry-Paraffin: Bcl-2 Antibody - IHC analysis of a formalin-fixed par...
Immunofluorescence (Paraffin-embedded Sections) (IF (p)) image for anti-B-Cell CLL/lymphoma 2 (BCL2) antibody (ABIN4283360) Immunohistochemistry-Paraffin: Bcl-2 Antibody - IHC analysis of a formalin-fixed par...
Product cited in: Chopra, Ray, Dwivedi, Tiwari, Singh, Singh, Kushwaha, Jahan, Pandey, Gupta, Chaturvedi, Pant, Ray, Gupta: "Photoprotective efficiency of PLGA-curcumin nanoparticles versus curcumin through the involvement of ERK/AKT pathway under ambient UV-R exposure in HaCaT cell line." in: Biomaterials, Vol. 84, pp. 25-41, 2016 (PubMed). Further details: Western Blotting

Huang, Huang, Gou, Wang, Liao, Wang: "Combretastatin A-4 Analogue: A Dual-Targeting and Tubulin Inhibitor Containing Antitumor Pt(IV) Moiety with a Unique Mode of Action." in: Bioconjugate chemistry, Vol. 27, Issue 9, pp. 2132-48, 2016 (PubMed). (Sample species: Human). Further details: Western Blotting

Krajewska, Rosenthal, Mikolajczyk, Stennicke, Wiesenthal, Mai, Naito, Salvesen, Reed, Fiskum, Krajewski: "Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation." in: Experimental neurology, Vol. 189, Issue 2, pp. 261-79, 2004 (PubMed). Further details: Western Blotting,Immunohistochemistry (Paraffin-embedded Sections)

Svingen, Karp, Krajewski, Mesner, Gore, Burke, Reed, Lazebnik, Kaufmann: "Evaluation of Apaf-1 and procaspases-2, -3, -7, -8, and -9 as potential prognostic markers in acute leukemia." in: Blood, Vol. 96, Issue 12, pp. 3922-31, 2000 (PubMed).

Ohta, Iwai, Kasahara, Taniguchi, Krajewski, Reed, Miyawaki: "Immunoblot analysis of cellular expression of Bcl-2 family proteins, Bcl-2, Bax, Bcl-X and Mcl-1, in human peripheral blood and lymphoid tissues." in: International immunology, Vol. 7, Issue 11, pp. 1817-25, 1996 (PubMed).

Krajewski, Bodrug, Krajewska, Shabaik, Gascoyne, Berean, Reed et al.: "Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in ..." in: The American journal of pathology, Vol. 146, Issue 6, pp. 1309-19, 1995 (PubMed).

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