SQSTM1 antibody (Sequestosome 1) (AA 300-440)

Details for Product anti-SQSTM1 Antibody No. ABIN4343147, Supplier: Log in to see
Antigen
  • SQSTM1
  • sqstm1
  • MGC79491
  • A170
  • OSIL
  • PDB3
  • ZIP3
  • p60
  • p62
  • p62B
  • OSF-6
  • Osi
  • STAP
  • ZIP
  • sb:cb621
  • zgc:85784
  • sequestosome 1
  • sqstm1 protein
  • SQSTM1
  • LOC100342157
  • sqstm1
  • Sqstm1
Alternatives
anti-Human SQSTM1 antibody for Immunohistochemistry (Frozen Sections)
Epitope
AA 300-440
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40
22
19
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18
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5
5
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2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
331
151
100
8
5
5
5
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4
2
2
2
2
2
1
1
1
1
1
1
Host
Rabbit
256
68
4
3
Clonality
Polyclonal
Conjugate
This SQSTM1 antibody is un-conjugated
18
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17
11
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8
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2
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2
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1
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1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Simple Western (SimWes), Western Blotting (WB)
264
137
95
85
79
64
52
35
32
14
13
4
3
3
2
Options
Supplier
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Supplier Product No.
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Immunogen A genomic peptide made to c-t of the human p62/SQSTM1 protein (within residues 300-440). [Swiss-Prot Q13501]
Purification Immunogen affinity purified
Alternative Name p62/SQSTM1 (SQSTM1 Antibody Abstract)
Background Gene Symbol: SQSTM1
Gene ID 8878
UniProt Q13501, Q64337, O08623
Pathways NF-kappaB Signaling, Neurotrophin Signaling Pathway, Autophagy
Application Notes Western Blot 1:1000, Simple Western 1:25, Immunohistochemistry, Immunocytochemistry/Immunofluorescence 1:25-1:200, Immunohistochemistry-Paraffin, Immunohistochemistry-FrozenUse of this antibody in IHC-Frozen is reported in PMID 25014022 and in IHC-paraffin is reported in PMID 27497324. In Simple Western only 10 - 15 μL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer PBS
Buffer contains: 0.02 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Sequestosome 1 (SQSTM1) (AA 300-440) antibody (ABIN4343147) Western Blot: p62/SQSTM1 Antibody [NBP1-48320] - Cultured HeLa cells were treated wit...
Immunofluorescence (IF) image for anti-Sequestosome 1 (SQSTM1) (AA 300-440) antibody (ABIN4343147) Immunocytochemistry/Immunofluorescence: p62/SQSTM1 Antibody [NBP1-48320] - Immunocyto...
Simple Western (SimWes) image for anti-Sequestosome 1 (SQSTM1) (AA 300-440) antibody (ABIN4343147) Simple Western: p62/SQSTM1 Antibody [NBP1-48320] - Simple Western lane view shows a s...
Product cited in: Eritja, Chen, Rodríguez-Barrueco, Santacana, Gatius, Vidal, Martí, Ponce, Bergadà, Yeramian, Encinas, Ribera, Reventós, Boyd, Villanueva, Matias-Guiu, Dolcet, Llobet-Navàs: "Autophagy orchestrates adaptive responses to targeted therapy in endometrial cancer." in: Autophagy, Vol. 13, Issue 3, pp. 608-624, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Su, Chu, Liao, Wang, Jan, Lin, Wu, Tseng, Yen, Huang: "Phellinus linteus Mycelium Alleviates Myocardial Ischemia-Reperfusion Injury through Autophagic Regulation." in: Frontiers in pharmacology, Vol. 8, pp. 175, 2017 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Rat (Rattus)).

Kim, Jeong, Nah, Yoo, Lee, Kim, Moon, Hong, Jung: "Pimozide reduces toxic forms of tau in TauC3 mice via 5' adenosine monophosphate-activated protein kinase-mediated autophagy." in: Journal of neurochemistry, Vol. 142, Issue 5, pp. 734-746, 2017 (PubMed). Method employed by authors: Western Blotting (WB)

Lin: "In Vitro and in Vivo Atheroprotective Effects of Gossypetin against Endothelial Cell Injury by Induction of Autophagy." in: Chemical research in toxicology, Vol. 28, Issue 2, pp. 202-15, 2016 (PubMed).

Katzenell, Leib: "Herpes simplex virus and interferon signaling induce novel autophagic clusters in sensory neurons." in: Journal of virology, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Sidjanin, Park, Ronchetti, Martins, Jackson: "TBC1D20 mediates autophagy as a key regulator of autophagosome maturation." in: Autophagy, Vol. 12, Issue 10, pp. 1759-1775, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Tan, Ho, Cho, Yu, Hung, Yu: "Fucosylation of LAMP-1 and LAMP-2 by FUT1 correlates with lysosomal positioning and autophagic flux of breast cancer cells." in: Cell death & disease, Vol. 7, Issue 8, pp. e2347, 2016 (PubMed). (Sample species: Human). Further details: Western Blotting

Song, Lee, Lim, Kim, Jang, Choi, Han: "Vibrio vulnificus VvhA induces autophagy-related cell death through the lipid raft-dependent c-Src/NOX signaling pathway." in: Scientific reports, Vol. 6, pp. 27080, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Kim, Lee, Gabr, Choi, Kim, Ko, Han: "Aβ-Induced Drp1 phosphorylation through Akt activation promotes excessive mitochondrial fission leading to neuronal apoptosis." in: Biochimica et biophysica acta, Vol. 1863, Issue 11, pp. 2820-2834, 2016 (PubMed). Method employed by authors: Western Blotting (WB) (Sample species: Human).

Wang, Lin, Chang, Liu, Li, Kuo, Hsieh, Lee: "Hinokitiol induces autophagy in murine breast and colorectal cancer cells." in: Environmental toxicology, Vol. 31, Issue 1, pp. 77-84, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Rožman, Yousefi, Oberson, Kaufmann, Benarafa, Simon: "The generation of neutrophils in the bone marrow is controlled by autophagy." in: Cell death and differentiation, Vol. 22, Issue 3, pp. 445-56, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Sun, Chen, Tu, Wang, Chang, Li: "MicroRNA-20a regulates autophagy related protein-ATG16L1 in hypoxia-induced osteoclast differentiation." in: Bone, Vol. 73, pp. 145-53, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Yao, Jia, Khan, Lin, Mitter, Boulton, Dunaief, Klionsky, Guan, Thompson, Zacks: "Deletion of autophagy inducer RB1CC1 results in degeneration of the retinal pigment epithelium." in: Autophagy, Vol. 11, Issue 6, pp. 939-53, 2015 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

Lin, Jan, Kuo: "Exploring MicroRNA Expression Profiles Related to the mTOR Signaling Pathway in Mouse Embryonic Fibroblast Cells Treated with Polyethylenimine." in: Molecular pharmaceutics, Vol. 12, Issue 8, pp. 2858-68, 2015 (PubMed).

Dever, Rodriguez, Lapierre, Costin, El-Hage: "Differing roles of autophagy in HIV-associated neurocognitive impairment and encephalitis with implications for morphine co-exposure." in: Frontiers in microbiology, Vol. 6, pp. 653, 2015 (PubMed). Further details: Immunocytochemistry,Immunofluorescence

Schwab, Ebert: "Neurite Aggregation and Calcium Dysfunction in iPSC-Derived Sensory Neurons with Parkinson's Disease-Related LRRK2 G2019S Mutation." in: Stem cell reports, Vol. 5, Issue 6, pp. 1039-52, 2015 (PubMed). (Sample species: Human). Further details: Western Blotting

Nicks, Lee, Harris, Falk, Todd, Arredondo, Dunn, Notterpek: "Rapamycin improves peripheral nerve myelination while it fails to benefit neuromuscular performance in neuropathic mice." in: Neurobiology of disease, Vol. 70, pp. 224-36, 2014 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting,Immunohistochemistry (Frozen Sections)

Fujiya, Konishi, Mohamed Kamel, Ueno, Inaba, Moriichi, Tanabe, Ikuta, Ohtake, Kohgo: "microRNA-18a induces apoptosis in colon cancer cells via the autophagolysosomal degradation of oncogenic heterogeneous nuclear ribonucleoprotein A1." in: Oncogene, Vol. 33, Issue 40, pp. 4847-56, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting

Rao, Tortola, Perlot, Wirnsberger, Novatchkova, Nitsch, Sykacek, Frank, Schramek, Komnenovic, Sigl, Aumayr, Schmauss, Fellner, Handschuh, Glösmann, Pasierbek, Schlederer, Resch, Ma, Yang, Popper et al.: "A dual role for autophagy in a murine model of lung cancer. ..." in: Nature communications, Vol. 5, pp. 3056, 2014 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunohistochemistry (Paraffin-embedded Sections)

Lee, Lin, Liu, Chang, Hsieh, Wang: "Salmonella induce autophagy in melanoma by the downregulation of AKT/mTOR pathway." in: Gene therapy, Vol. 21, Issue 3, pp. 309-16, 2014 (PubMed). (Sample species: Mouse (Murine)). Further details: Western Blotting

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